A life-changing victory is within grasp for the PGA Tour players set to tee off Thursday in the 2022 Bermuda Championship at Port Royal Golf Club. The tournament has been granted full status, meaning the winner in Southampton, Bermuda earns a tour exemption through 2025 and invitations to the Masters and PGA Championship, as well as 500 FedEx Cup points. With all of the world's top players taking the week off after competing in last week's CJ Cup, it's a prime opportunity for a lesser-known player. Lucas Herbert won his first PGA Tour title in this tournament last year, and the previous two winners – Brendon Todd in 2019 and Brian Gay in 2020 – both snapped PGA Tour victory droughts of well over five years. Herbert won't return to defend his title, leaving the likes of Denny McCarthy, Patrick Rodgers and 2021 PGA Tour winners Seamus Power and Garrick Higgo to battle it out. John Daly is scheduled to compete on a sponsor exemption. 

McCarthy (18-1) is the favorite in the latest 2022 Bermuda Championship odds. Mark Hubbard (22-1) and Rodgers (22-1), who finished fourth last year, also are top contenders in the Bermuda Championship field. They are ahead of a large group at 25-1 that includes Power, Thomas Detry and Adrian Meronk. Daly is a massive 1000-1 longshot. Before you lock in any 2022 Bermuda Championship picks or predictions, you need to check out the PGA Tour best bets and sleepers from SportsLine golf insider Patrick McDonald.

After spending time at FanSided and NBC Sports EDGE, McDonald joined CBS Sports as a golf writer in the spring of 2022. Now covering the sport from a broader perspective, McDonald still likes to dip his toes into the betting pools on a weekly basis on the PGA Tour. 

He takes a measured approach to his outright picks and finished the 2021-22 season up 42 units on those plays, having hit Cameron Smith (22-1) at the Tournament of Champions, Hudson Swafford (250-1) at The American Express, Joaquin Niemann (70-1) at the Genesis Invitational and Justin Thomas (66-1) live at the PGA Championship.

At this year's Zozo Championship, McDonald nailed a first-round leader, backing 80-1 Brendan Steele before he closed with four birdies to lead by one stroke after Thursday's round. The expert also hit two of his three matchup plays there, including tournament winner Keegan Bradley over Corey Conners, one of the pre-tournament favorites. Then last week at the CJ Cup, McDonald was all over defending champion Rory McIlroy, who would go on to win the tournament and defend his title. Anyone who followed McDonald's golf betting advice has cashed in huge.

Now, McDonald has studied the 2022 Bermuda Championship field and is locking in his best bets, top sleepers and favorites to avoid. You can head to SportsLine now to see all his PGA picks and predictions

Top 2022 Butterfield Bermuda Championship expert picks

Shockingly, McDonald is backing away from the favorite, fading McCarthy even though he was a contender several times last season. The problem is, contending isn't the same as winning, and he doesn't have a PGA Tour victory. He had five top-10 finishes in 2021-22, including a T-7 at the U.S. Open. He finished second on tour in strokes gained putting and 36th in strokes gained around the green, but he hasn't found the same success this fall. The 29-year-old has missed the cut three times and finished in the top 20 just once in his past seven PGA Tour events.   

On the other hand, Callum Tarren (55-1) has been steady in several key areas, even if his results haven't shown it yet. The Englishman is in the top 20 among these players in strokes gained off the tee, approach and putting. The 32-year-old also is third among this group in par-4 scoring average (3.89), his length should give him an edge on the par-5's and most players will struggle on the tough par-3's at Port Royal. He did post a T-13 finish at the Sanderson Farms this season, so he can score low, and McDonald expects Tarren to get rolling in Bermuda. See who else to pick here.

How to make 2022 Bermuda Championship golf picks

Before this week's PGA Tour event, McDonald has locked in his best bets for the 2022 Bermuda Championship. He has several outright plays, including a monster longshot that would bring a massive payout of 100-1. You can only find out who it is, and get the rest of McDonald's PGA picks and analysis, at SportsLine

So which 2022 Bermuda Championship picks should you target? Which golfer priced at 100-1 could pull off a stunning victory this week at Bermuda Championship 2022? Check out the odds below, then visit SportsLine to see Patrick McDonald's top prop picks for Bermuda Championship 2022, all from the expert who ended last season up 42 units on outright plays, and find out.

2022 Butterfield Bermuda Championship odds, field

See full Butterfield Bermuda Championship 2022 picks, best bets, and predictions here

Denny McCarthy +1600
Thomas Detry +1600
Seamus Power +1800
Nick Hardy +2000
Adrian Meronk +2100
Mark Hubbard +2400
Justin Lower +2400
Patrick Rodgers +2800
Aaron Rai +2800
Russell Knox +3100
Seonghyeon Kim +3100
Robby Shelton +3300
Alex Smalley +3400
Stephan Jaeger +3700
Nick Taylor +3700
Greyson Sigg +4000
Callum Tarren +4100
Will Gordon +4200
Lucas Glover +5000
Byeong Hun An +5000
Joseph Bramlett +5000
Adam Long +5000
Adam Schenk +5000
Ze-Cheng Dou +5000
Garrick Higgo +5000
Brandon Wu +5000
Harry Hall +5000
Chun-an Yu +5000
Cameron Percy +5000
Sam Ryder +5500
Michael Gligic +6000
Chesson Hadley +6000
Erik Van Rooyen +6000
Peter Malnati +6500
C.T. Pan +6500
Sam Stevens +6500
Doug Ghim +6500
Henrik Norlander +6500
Ryan Armour +6500
Tyler Duncan +6500
Matthias Schwab +8000
Charley Hoffman +8000
Kramer Hickok +8000
Vincent Norrman +8000
Scott Piercy +8000
Chad Ramey +8000
MJ Daffue +8000
Hank Lebioda +8000
Brian Gay +9500
Nate Lashley +9500
Austin Eckroat +9500
Brian Stuard +9500
Austin Smotherman +9500
Brice Garnett +9500
Robert Streb +11000
Matthias Schmid +11000
Fabian Gomez +11000
Luke Donald +11000
Ben Taylor +11000
Harrison Endycott +12000
Ben Griffin +12000
Cody Gribble +12000
Ben Martin +12000
Michael Kim +12000
Austin Cook +12000
William McGirt +12000