There are multiple NCAA Tournament Cinderella teams every season, and there are sure to be more in the 2024 NCAA Tournament bracket. Saint Peter's burst onto the scene two years ago, becoming the only No. 15 seed ever to advance to the Elite Eight. The Peacocks are back in the 2024 March Madness bracket as a No. 15 seed and will enter the Big Dance full of confidence after winning eight of their last 10 games. Saint Peter's will square off against No. 2 Tennessee in the first round of the 2024 NCAA Tournament.

The Volunteers haven't advanced past the Sweet 16 since 2010. Should your 2024 March Madness bracket picks include backing the Peacocks to pull off a stunning upset in the first round, or should you back another double-digit seed like Nevada (10), James Madison (12) or Samford (13) to make a deep run? Before you make your 2024 NCAA Tournament predictions, see the March Madness bracket picks from the proven computer model at SportsLine.

This model, which simulates every game 10,000 times, has nailed 20 first-round upsets by double-digit seeds since its inception in 2016 and nailed UConn's dramatic Final Four run as a 4-seed last year. It went an amazing 22-10 in the first round, including an astounding 12-4 in the Midwest and West regions.

Last year, SportsLine's computer simulation nailed massive upsets, including huge wins by No. 13 Furman over No. 4 Virginia and No. 10 Penn State over No. 7 Texas A&M. The model has beaten over 92% of all CBS Sports bracket players in three of the past five tournaments.

Now, SportsLine's advanced computer model has simulated the entire 2024 NCAA Tournament 10,000 times to come up with the perfect 2024 NCAA Tournament bracket and find out which teams will pull off the biggest upsets. You shouldn't even think about making a pick without seeing what their model has to say.

Top 2024 March Madness bracket upset picks

One Midwest Region surprise the model has identified: No. 11 seed Oregon knocks off No. 6 seed South Carolina. The Ducks reeled off three consecutive victories to be crowned champions of the Pac-12 Tournament. Oregon is led by Jermaine Couisnard, who's averaging 15.4 points, 3.3 assists and 1.6 steals per game.

Center N'Faly Dante is expected to have a big day when the Ducks take the court on Thursday. The 6-foot-11 senior averages 16.2 points and 8.8 rebounds per game while knocking down 70.2% of his field goal attempts. South Carolina ranks outside the top 200 in defensive rebounds and blocks, which could be an issue against Dante and the Ducks. With the Gamecocks also ranking 64th out of 68 tournament teams in creating turnovers, that presents more possessions for Oregon and more opportunities for Dante to make his presence felt.

Another Midwest Region surprise the model has identified: No. 5 Gonzaga beats No. 4 Kansas to advance to the Sweet 16. The Bulldogs have four players averaging in double-figures, including forward Anton Watson. The 6-foot-8 senior enters March Madness 2024 averaging 14.1 points and 7.1 rebounds per game while knocking down 57.7% of his field goals.

As a team, the Zags are making 57.2% of their field goals, which ranks eighth in the nation. That's a big reason why Gonzaga is scoring 84.9 points per game on average, the seventh-most in college basketball. Meanwhile, the Jayhawks are making just 32.9% of their 3-pointers this season, which ranks 237th in the country. Bill Self's squad will also be without leading scorer Kevin McCullar Jr. due to a knee injury in the NCAA Tournament. See which other 2024 March Madness matchups to target here.

How to make 2024 NCAA Tournament bracket predictions

Who wins every tournament-defining matchup? And which teams will make surprising runs through the 2024 NCAA Tournament bracket? With the model's track record of calling bracket-busting upsets, you'll want to see which stunners it's calling this year before locking in any 2024 NCAA bracket picks.

So what's the optimal NCAA Tournament 2024 bracket? And which NCAA Tournament Cinderella teams will shock college basketball? Visit SportsLine to see which 12-seed reaches the Sweet 16, and which region features a 10-seed, 11-seed, and 13-seed delivering first-round shockers and has a 9-seed in the Elite Eight, all from the model that has beaten 92% of bracket players three of the last five tournaments.