NCAA Basketball: West Virginia at Kansas
Denny Medley / USA TODAY Sports

A Big 12 battle is on tap Friday between the No. 8 West Virginia Mountaineers and the Iowa State Cyclones at 9 p.m. ET at WVU Coliseum. The Mountaineers are 6-1 overall and 2-0 at home, while Iowa State is 1-3 overall and 0-1 on the road. The Mountaineers are 5-1 against the spread in their last six games following a straight-up win. The Cyclones are 3-7 against the spread in their last 10 Friday games.

The Mountaineers are favored by 15 points in the latest West Virginia vs. Iowa State odds from William Hill Sportsbook, and the over-under is set at 144. Before making any Iowa State vs. West Virginia picks, you'll want to see the college basketball predictions and betting advice from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of almost $2,600 for $100 players on its top-rated college basketball picks against the spread. It's also off to a fast start in the 2020-21 season, going 8-4 on all its top-rated picks and returning well over $300. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on WVU vs. Iowa State. You can head to SportsLine to see its picks. Here are several college basketball odds for Iowa State vs. WVU:

  • West Virginia vs. Iowa State spread: West Virginia -15
  • West Virginia vs. Iowa State over-under: 144 points
  • West Virginia vs. Iowa State money line: West Virginia -1700, Iowa State +900
Latest Odds: West Virginia Mountaineers -15

What you need to know about West Virginia

The Mountaineers won their third straight game Sunday, downing visiting Richmond 87-71. Five West Virginia players scored in double digits, with Miles McBride leading the way with 20 points, Taz Sherman scoring 15, Oscar Tshiebwe and Sean McNeil each scoring 12 and Derek Culver chipping in 10.

McBride leads the Mountaineers with 14.6 points and 4.6 assists per game, with Culver pulling down 10.7 rebounds per outing.

What you need to know about Iowa State

The Cyclones dropped their third straight decision on Tuesday, losing 74-65 to Kansas State. Rasir Bolton scored 19 points for Iowa State in the loss.

Bolton leads Iowa State in scoring (15.8 ppg), rebounding (5.3 rpg) and assists (6.0 apg).

How to make West Virginia vs. Iowa State picks

The model has simulated West Virginia vs. Iowa State 10,000 times and the results are in. It is leaning under on the total, and it's also generated a point-spread pick that is hitting in well over 70 percent of simulations. You can only see the pick at SportsLine.

So who wins West Virginia vs. Iowa State? And which side of the spread cashes in well over 70 percent of simulations? Visit SportsLine now to find out which side of the Iowa State vs. West Virginia spread you need to jump on Friday, all from the model that has crushed its college basketball picks, and find out.