Novak Djokovic can inch closer to a 19th grand slam title when he squares off against Canadian Denis Shapovalov on Friday at approximately 10:30 a.m. ET in a 2021 Wimbledon semifinal at The All England Lawn Tennis Club. The 34-year-old Djokovic owns 18 career grand slam titles, including five at Wimbledon. He is only two grand slam titles behind all-time leaders Roger Federer and Rafael Nadal. On Friday he will meet Shapovalov, who will be playing in his first grand slam semifinal. The winner of Friday's match will advance to the final to face either Matteo Berrettini or Hubert Hurkacz. 

William Hill Sportsbook lists Djokovic as a -1400 favorite (risk $1,400 to win $100) in the latest Djokovic vs. Shapovalov odds, with Shapovalov listed at +700 as the underdog. You can also pick whether Djokovic will cover the 6.5-game spread and how many games the match will last (over-under of 33.5), among other wagering options in the 2021 Wimbledon odds. Before making any Shapovalov vs. Djokovic picks, you need to see the Wimbledon 2021 predictions from SportsLine tennis handicapper Sean Calvert.

Calvert is the renowned handicapper who called Stan Wawrinka winning the 2014 Australian Open at 60-1, the last Australian title won by someone other than Djokovic or Roger Federer. In 2019, Calvert took down a huge score on Dominic Thiem winning Indian Wells at 80-1. Anyone following his picks is way up.

Now, Calvert has scrutinized the latest Wimbledon 2021 odds and released his coveted best bets for Djokovic vs. Shapovalov. He's sharing his expert Wimbledon 2021 picks and analysis only at SportsLine.

Djokovic vs. Shapovalov preview

Djokovic has been nearly unbeatable with his serve at Wimbledon. In his five matches he has won 224 out of a possible 259 first serve points. His 86.5 percent conversion rate leads all men's players in the field of 128. He also has won 56.8 percent of his second serves, which ranks 18th in the field.

Djokovic also has been deadly with his return game. Through the quarterfinals, he has a return points win percentage of 44, best in the field. His return has helped him break his opponents 23 times, which ranks fourth even though he has played just 16 sets. 

How to make Djokovic vs. Shapovalov picks

Who will win the Djokovic vs. Shapovalow Wimbledon 2021 semifinal match? Calvert has two wagers, both that would pay more than 7-1. Be sure to check out Calvert's picks and analysis before making your Wimbledon 2021 bets for the men's semifinals.

Who wins Djokovic vs. Shapovalov in the 2021 Wimbledon men's semifinal? And what wagers does Calvert like? Visit SportsLine now to see Sean Calvert's best bets for Shapovalov vs. Djokovic, all from the famed tennis handicapper who called Wawrinka winning the 2014 Australian Open at 60-1, and find out.