Amanda Anisimova aims to continue an impressive run at the 2022 Wimbledon Championships on Wednesday. Anisimova takes on Simona Halep in a highly-intriguing quarterfinal match that will begin at approximately 8:30 a.m. ET. The top-20 seeds face off at All England Club in London. The winner will earn a berth in the semifinals with a wide-open field in the absence of top-seeded Iga Swiatek, who lost in the third round on Saturday to Alize Cornet. 

Caesars Sportsbook lists Halep as a -230 favorite (risk $230 to win $100) in the latest Halep vs. Anisimova odds, with Anisimova getting +175 (risk $100 to win $175) as the underdog. Caesars sets the over-under for total games at 21.5, with Halep favored by 3.5 games. Before making any 2022 Wimbledon picks or predictions, make sure you check out the expert tennis picks and analysis from SportsLine's Gavin Mair.

Mair is the international women's tennis expert who called unseeded Jelena Ostapenko (80-1) winning the 2017 French Open, Naomi Osaka (32-1) winning the 2018 U.S. Open, Bianca Andreescu (20-1) winning the 2019 U.S. Open, plus many other prescient calls. He also correctly backed Iga Swiatek to win the 2022 French Open in advance of the tournament.

Now, Mair has scrutinized the latest Wimbledon 2022 odds and released his coveted best bets. He's sharing all of his Wimbledon picks and analysis only at SportsLine.

Simona Halep vs. Amanda Anisimova preview

Halep is a veteran player with an impressive pedigree. The No. 16 seed is a two-time grand slam winner, taking home the 2018 French Open title and winning the 2019 Wimbledon championship. She is the only remaining grand slam winner in the women's draw, and the former No. 1 player in the world has an 11-match winning streak at All England Club. She dominated No. 4 seed Paula Badoa in the previous round, losing only three games, and Halep won 89 percent of points on her first serve. She also dismantled Anisimova just prior to Wimbledon, and Halep has the experience advantage.

Still, Anisimova is playing at a high level. She soundly defeated Harmony Tan in the fourth round, and the 20-year-old American has sky-high upside. She made a semifinal run at the 2019 French Open, defeating Halep in straight sets in the process. Anisimova has considerable power, and she showcased the entire package in a win over Coco Gauff in the third round at Wimbledon.

How to make 2022 Wimbledon women's quarterfinal picks

In addition to his overall analysis, Mair has released two strong bets: a play on the outright winner and whether the match goes over or under 21.5 games. Be sure to see Mair's picks and analysis before locking in your 2022 Wimbledon picks for the women's quarterfinals.

Who wins Halep vs. Anisimova in the 2022 Wimbledon women's quarterfinal? And what other pick could lead to a big return? Visit SportsLine now to see Mair's best bets for Halep vs. Anisimova, all from the famed tennis handicapper who has crushed his Grand Slam tennis picks, and find out.