The Kansas City Chiefs will face off against the San Francisco 49ers in a Super Bowl LVIII rematch on Sunday at Levi's Stadium. San Francisco is 3-3 overall and 2-1 at home, while Kansas City is 5-0 overall and 2-0 on the road. Both teams have had over a week to prepare for this matchup. The Chiefs, who had a bye in Week 6, beat the New Orleans Saints 26-13 in their last outing. The Niners beat the Seattle Seahawks 36-24 on Thursday Night Football in Week 6.
Kickoff in Santa Clara is at 4:25 p.m. ET. The 49ers are favored by 1.5 points in the latest 49ers vs. Chiefs odds from SportsLine consensus, and the over/under is 47 points. San Francisco is a -128 money-line favorite (risk $128 to win $100). Before locking in any Chiefs vs. 49ers picks, you'll want to see the NFL predictions and betting advice from the proven compute simulation model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 7 of the 2024 NFL season on an incredible 11-3 hot streak on top-rated NFL picks this year. Longer term, it is on a 192-132 roll on top-rated NFL sports betting picks that dates back to the 2017 season and a 46-24 roll on top-rated NFL picks since Week 7 of 2022.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it at their favorite betting sites or their best sports betting app is way up.
The model has set its sights on Chiefs vs. 49ers and just locked in its Week 7 NFL picks and predictions. You can head to SportsLine now to see the model's picks. Here are several NFL betting lines for the Niners vs. Chiefs game:
- 49ers vs. Chiefs spread: 49ers -1.5
- 49ers vs. Chiefs over/under: 47 points
- 49ers vs. Chiefs money line: 49ers -128, Chiefs: +108
- 49ers vs. Chiefs picks: See picks at SportsLine
- 49ers vs. Chiefs streaming: FuboTV (Try for free)
Why the Chiefs can cover
The Chiefs are now riding an 11-game winning streak dating back to last season after beating the Saints 26-13 last time out. Kareem Hunt has helped solidify the backfield in the absence of Isiah Pacheco (fibula). Hunt rushed for 102 yards and a touchdown in the win over New Orleans, while Patrick Mahomes threw for 331 yards.
The Chiefs were moving up and down the field and finished the game with 460 total yards. That's the most total yards they've posted since October of last year. Kansas City continues to be one of the best teams for bettors to back against the spread, going 17-8-1 ATS since the start of last year, the second-best mark in the league, behind only the Lions. See which team to pick here.
Why the 49ers can cover
Meanwhile, the Niners walked away with a 36-24 win over the Seahawks last Thursday to help bounce back from a 24-23 upset loss to the Cardinals the prior week. Brock Purdy was sharp leading his team to the win, throwing for 255 yards and three touchdowns. George Kittle was another key player, picking up 58 receiving yards and two touchdowns.
The Niners got some good injury news on Friday as running back Jordan Mason (shoulder) and receiver Deebo Samuel (wrist) did not receive injury designations. The Chiefs, meanwhile, continue to be without the playmaking trio of Pacheco, Rashee Rice (knee) and Hollywood Brown (shoulder). See which team to pick here.
How to make 49ers vs. Chiefs picks
The model has simulated 49ers vs. Chiefs 10,000 times and the results are in. The model is leaning Over on the point total, and it's also generated a point-spread pick that hits in over 50% of simulations. You can only see the model's pick at SportsLine.
So who wins Chiefs vs. 49ers on Sunday, and which side of the spread hits over 50% of the time? Visit SportsLine right now to see which side of the 49ers vs. Chiefs spread you should be all over Sunday, all from the model on a 192-132 roll on its top-rated NFL picks, and find out.