Caldwell-Pope hit three of his eight three-point attempts and came up with eight rebounds, two steals and one assist. His scoring total was one point off of his season-high of 28, set on Jan. 31 against the Rockets.
Detroit is a 6 1/2-point home favorite against Boston.
"Hopefully, it's a short-term thing, because we need him," Van Gundy said, via the Detroit Free Press. "Nothing you want to fool around with."
Caldwell-Pope said the injury occurred the game before and that he exited Wednesday's game since he didn't feel 100 percent on the court.
"I wanted to come back, but just to be on the safe side, I just sat the game out," Caldwell-Pope said. "I didn't want to keep injuring it. It's not going to be long. Do treatments [Thursday] and see how it feels Friday."
Caldwell-Pope played three minutes before exiting with the issue and was 1 of 1 from 3-point range. The Pistons next play Friday against the Nuggets.
Caldwell-Pope delivered the second-best scoring performance in his career thanks to his success from behind the arc, making six three-pointers in one game after managing only five in his previous five games combined.
''I felt good,'' Caldwell-Pope said after the game, per the Associated Press. ''I got myself going with my energy on the defensive end, ran the floor to get easy baskets and that opened up my outside shooting.''
Caldwell-Pope also racked up five rebounds, four assists, three blocks and one steal in 40 minutes of action. The Pistons will face the Heat Tuesday.
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