Fermin was removed from Wednesday's game against the Mariners with an apparent injury,Jeff Sanders of The San Diego Union-Tribune reports.

Fermin was immediately pulled from the game after taking a Brendan Donovan foul tip off his mask in the third inning. He'll presumably be evaluated for a concussion; meanwhile, Luis Campusano will take over behind the plate and start any games that Fermin may have to miss.

Naylor went 1-for-3 with a double and two RBI in Wednesday's 5-3 loss to St. Louis.

Naylor closed a deficit to one run in the seventh inning with a two-run double. Those were the first RBI of the season for the catcher, who entered the game batting .143. Based on his strong finish to the 2025 season, when Naylor was a key driver (.862 OPS, 16 RBI) in a September push for the playoffs, the Guardians expected him to take a leap in 2026.

Del Castillo went 2-for-5 with a triple, a home run and five RBI in Wednesday's 8-5 extra-inning win over the Orioles.

Getting the start at catcher and batting cleanup, Del Castillo nearly slugged a homer to left-center field in the third inning, instead settling for his first career triple. The 26-year-old left no doubt in the top of the 10th when he crushed a Tyler Wells fastball 420 feet to right-center for a two-run blast that broke open a 5-5 tie. It was Del Castillo's first long ball of the season, and through his first seven games of 2026 he's batting .346 (9-for-26) with 10 RBI.

Heineman (back) is out of the lineup for Wednesday's game against the Brewers.

Brandon Valenzuela will draw a fifth consecutive start at catcher while Heineman recovers from back spasms, but the Blue Jays' willingness to use Heineman off the bench in Tuesday's 9-7 extra-inning win suggests that he could soon be ready to catch a full game. Heineman caught the final three innings of Tuesday's contest and flied out in his lone at-bat.

Ballesteros is out of the lineup for Wednesday's game against the Phillies.

Ballesteros had served as the Cubs' designated hitter in six of the past seven games but will be riding pine Wednesday while the Phillies send a tough lefty (Jesus Luzardo) to the hill. Seiya Suzuki will get a day off from playing the outfield and will draw the start at DH in the series finale.

Kelly is out of the lineup for Wednesday's game against the Phillies.

Miguel Amaya will step in behind the plate for Kelly, who will be rested after making starts in each of the past three days. Kelly is off to a scorching start to April, having recorded a hit in each of his starts while slashing .364/.488/.545 in 10 games overall.

Polanco isn't in the lineup for Wednesday's game against the Dodgers due to pain related to his Achilles bursitis, Laura Albanese of Newsday reports.

Wednesday will mark the third game Polanco has missed in the past week while battling an Achilles issue that has bothered him since the regular season began. Manager Carlos Mendoza said the Mets may place the 32-year-old on the injured list, but the team will wait to see how he feels ahead of Friday's series opener against the Cubs before making a decision.

The Mets placed Young on the 10-day injured list Wednesday, retroactive to Monday, due to a meniscus tear in his left knee.

Young reported discomfort in his left knee Tuesday, and further imaging revealed a more severe injury that will result in the 30-year-old undergoing surgery, per Will Sammon of The Athletic. It's a significant blow to the Mets' depth at first base and in the outfield, especially with Juan Soto (calf) still on the 10-day IL. Young is looking at a lengthy absence depending on the extent of the surgery needed to repair the tear, which could have him sidelined until the summer.

The White Sox designated Harris for assignment Wednesday.

Harris will cede his spot on the 40-man roster and 26-man active roster to one of the organization's top prospects in Sam Antonacci, who received a call-up from Triple-A Charlotte. After receiving a promotion of his own from Charlotte on April 7, Harris proceeded to go 3-for-12 with a double, two stolen bases and a 4:1 BB:K in six games for the White Sox. He'll now go through the waiver process and will have the ability to elect free agency if he goes unclaimed.

Hoskins is out of the lineup for Wednesday's game against the Cardinals.

Since the calendar flipped to April, Hoskins has slashed just .152/.222/.333 with a 27.8 percent strikeout rate over nine games. As a result of his ongoing struggles, Hoskins will be left out of the lineup for the second straight day, with both of his absences coming against right-handed starting pitchers. Hoskins should still be a mainstay in the starting nine versus southpaws, but Guardians manager Stephen Vogt may prefer to use Kyle Manzardo at first base and a rotation of players at the designated-hitter spot against righties.

Stewart went 1-for-3 with a solo home run in Tuesday's 2-1 win over the Giants.

His fourth-inning shot off Robbie Ray ended up being the game-winning hit. Stewart has left the yard in three of the last six games, continuing an impressive start to his first full MLB season that has seen him compile a .310/.431/.638 slash line with five homers, three steals, 11 runs and 11 RBI in 17 contests, as well as more walks (13) than strikeouts (12).

Steer went 1-for-3 with a solo home run in Tuesday's 2-1 win over San Francisco.

Steer's third-inning shot gave the Reds an early lead in a game where offense was at a premium. Cincinnati managed just three hits and two were solo home runs. It was the second homer in three games for Steer, who's fighting back from a 1-for-17 (.059) start to the season. Since then, he's gone 9-for-37 (.243) with three doubles, three home runs and four RBI over 10 contests.

Hoerner went 3-for-5 with a home run, an additional run scored, a stolen base and five RBI in Wednesday's 11-2 win over the Phillies.

Hoerner's scorching-hot start to the season continued, as he delivered his third three-hit effort through 18 games and launched his second home run. The infielder is also a perfect 6-for-6 in stolen bases, and he's batting a robust .324 with a .917 OPS. At this rate, Hoerner appears primed to make his first All-Star Game appearance in a few months, and he seems locked in as Chicago's preferred leadoff hitter against both righties and lefties.

Marte served as the designated hitter and went 1-for-5 with a run scored in Wednesday's 8-5 win over Baltimore.

Marte, who was scratched from the lineup Tuesday due to tightness in his lower back, returned to action but not to second base. He'll get another break from playing the field Thursday, when the Diamondbacks are off.

Altuve is out of the lineup for Wednesday's game against the Rockies.

Per Matt Kawahara of the Houston Chronicle, manager Joe Espada said that Altuve's absence from the lineup is a routine rest day after the 35-year-old infielder started each of Houston's first 18 games. Isaac Paredes will spell Altuve at second base and will bat third.

Vivas will start at second base and bat seventh in Wednesday's game against the Pirates.

He'll stick in the lineup for a fourth straight game, this time shifting over to the keystone after manning third base in each of the previous three contests. While the left-handed-hitting Vivas' playing time against left-handed pitching is likely to remain more variable, he might have earned himself more frequent opportunities to start versus righties after getting on base at a .406 clip in 33 plate appearances against them so far in 2026.

Nunez is out of the lineup for Wednesday's game against the Pirates.

Jorbit Vivas will fill in at second base for Nunez, who will head to the bench after a stretch of four consecutive starts. Nunez is batting just .212 with one extra-base hit over 58 plate appearances, but he's provided value for fantasy managers who have rostered him primarily for his speed (seven steals in eight attempts).

Frazier will start at second base and bat ninth in Wednesday's game against the Yankees, Erica Weston of Bally Sports West reports.

For the Angels' third straight matchup versus a right-handed starting pitcher (Luis Gil), Frazier will receive the nod at second base. Over a limited sample of 26 plate appearances this season, Frazier has produced a strong .848 OPS, so he could hold the edge at keystone over Oswald Peraza and Vaughn Grissom until his bat inevitably cools down.

McKinstry was removed from Wednesday's game against the Royals after colliding with Jac Caglianone in the seventh inning, Cody Stavenhagen of The Athletic reports.

A grounder to third base put McKinstry in the path of the running Caglianone, causing the former to trip and come up favoring his left leg. The severity of McKinstry's injury remains unknown, but any missed time would open up more opportunities for Gleyber Torres to start at second base and Colt Keith at third.

Monasterio started at first base and went 3-for-5 with a double, an RBI and a run scored in Wednesday's 9-5 win over Minnesota.

Monasterio, who stepped in at first base Tuesday when Willson Contreras was removed due to a back issue, started there Wednesday. The three-hit day was the first multi-hit effort of the season for Monasterio, who entered the contest batting .143 (2-for-14) in limited playing time. The Red Sox are off Thursday, which gives Contreras downtime ahead of the four-game set with the Tigers begins Friday.

Burger isn't in the lineup for Wednesday's game against the Athletics.

Burger will get a day to rest Wednesday after going 3-for-8 with two homers and five RBI through the first two games of the series. Joc Pederson will fill in for him at first base, moving Wyatt Langford into the DH spot while Ezequiel Duran patrols left field.

Karros is out of the lineup for Wednesday's game against the Astros.

Willi Castro will cover third base while Karros receives a breather Wednesday. Karros had started in each of the Rockies' previous four games, going 2-for-11 with two walks and a run.

Tena is out of the lineup for Wednesday's game against the Pirates.

Tena has started in just one of the Nationals' last six games, sitting on three occasions against left-handed starters and twice against righties. The 25-year-old has posted a modest .665 OPS over 28 plate appearances on the season and may have to settle for more of a part-time role if Washington elects to open up playing time for Jorbit Vivas (.814 OPS in 40 plate appearances).

Williamson is absent from the lineup for Wednesday's game versus the White Sox.

He had two doubles and plated three runs in Tuesday's win over the White Sox, but he finds himself on the bench a day later. Williamson and Richie Palacios have shared second base for the Rays this season and it will be Palacios handling the keystone Wednesday.

Shaw went 3-for-4 with three doubles, two runs scored and three RBI in Wednesday's 11-2 win over the Phillies.

Shaw got into a nice groove Wednesday as he delivered his first three-hit effort of the season and doubled his extra-base hit total. The 24-year-old also raised his batting average from .200 to .245 in the process. Shaw has seen his playing time trend down with Seiya Suzuki back from the injured list, though the former can still provide some fantasy value from a super utility role due to his ability to hit for power and swipe a base.

Swanson went 3-for-5 with a solo home, an additional run scored and two total RBI in Wednesday's 11-2 win over the Phillies.

Swanson appears to be heating up, as he now has three home runs across his last four games. The shortstop's batting average is still sitting at just .200, but his recent surge suggests that figure will continue to climb. Swanson has also yet to sit out a game this season, and his consistent playing time should offer him plenty of opportunities to keep racking up counting stats while he's locked in at the plate.

Baez went 1-for-3 with a double and a run scored in Wednesday's 2-1 win over the Royals.

Baez started in center field for the third time in Detroit's last five games, and he continued his solid start to the season. The veteran is now batting .295 with a .774 OPS, one home run, five RBI and five runs scored across 13 appearances. Baez's ability to play the outfield has opened up shortstop for young phenom Kevin McGonigle, and that arrangement figures to stick for the time being, though McGonigle can also shift over to third to allow Baez to cover short on occasion.

Perez went 1-for-1 with a solo home run in Wednesday's 2-1 win over the Royals.

Perez entered the game as a defensive replacement after Zach McKinstry left following a collision, and the former didn't come to the plate until the eighth inning. He made the at-bat count, however, as the outfielder lifted his first home run of the year to break a 1-1 tie. It was a positive moment for Perez, though he still looks like a reserve option for the Tigers after getting recalled from Triple-A Toledo last week.

Story went 2-for-4 with a walk, a double, a home run and five RBI in Wednesday's 9-5 win over the Twins.

The veteran shortstop capped a five-run third inning with a three-run shot off Simeon Woods Richardson before adding a two-run double in the sixth. The long ball was Story's first in April and second of the season, and while he had a sluggish start to the campaign he appears to have found his groove -- over the last nine games he's batting .314 (11-for-35) with a whopping 15 RBI.

Jackson went 2-for-5 with a home run and three RBI in Wednesday's 8-5 extra-inning loss to the Diamondbacks.

The 26-year-old utility player got hold of an Eduardo Rodriguez fastball in the bottom of the fourth inning, ripping it on a line over the fence in left-center field for a two-run shot. It was Jackson's fourth homer of the season, and all four have come in the last five games as part of a six-game hitting streak, during which he's batting .480 (12-for-25) with two doubles, five runs and 10 RBI. With Jackson Holliday (hand) having had a setback on his rehab assignment earlier this week and Jordan Westburg (elbow) still not expected back until late May, Jackson has the starting job at second base locked down for now.

Valera started in left field and went 1-for-2 with a double in Wednesday's 5-3 loss to the Cardinals.

Valera started a second consecutive game since being activated off the injured list Monday. Both starts have come against right-handers, and the outfielder was pinch hit for in the seventh inning of Wednesday's contest when he was about to face a left-hander. Valera is 2-for-6 with a pair of doubles and RBI in his two games.

Kiner-Falefa started at third base and went 2-for-3 with a walk and a run scored in Wednesday's 9-5 win over the Twins.

Kiner-Falefa, who filled in for the resting Caleb Durbin, made a second consecutive start. His start Tuesday came at second base against a left-hander as part of a platoon role with Marcelo Mayer. Kiner-Falefa's playing time has been sporadic, which hurts his offense. He entered Wednesday's contest batting .133 (2-for-15).

Church went 3-for-4 with a double, two runs scored, an RBI and a stolen base in Wednesday's 5-3 win over the Guardians.

He also made an impact defensively, recording an outfield assist as Kyle Manzardo was thrown out at home plate in the fourth inning after a George Valera double got over Church's head. The steal was Church's first of the season -- part of a 4-for-4 performance on the basepaths by the Cardinals against the battery of Slade Cecconi and Bo Naylor -- and the multi-hit effort was his first since Opening Day. Despite the big afternoon, however, the 25-year-old Church is slashing just .205/.238/.308 through 16 games on the season.

Trammell is out of the lineup for Wednesday's game against the Rockies.

After getting called up from Triple-A Sugar Land on Friday, Trammell has started in three of the Astros' ensuing six games while going a collective 4-for-13 with a double, two walks, three RBI and two runs. He'll likely be part of a timeshare in center field with Joey Loperfido until Jake Meyers (oblique) is ready to return from the injured list.

Doyle is out of the lineup for Wednesday's game against the Astros.

With Doyle taking a seat for the third time in eight games, Jake McCarthy will pick up a start in center field. Though Doyle's status as a two-time Gold Glove Award winner aids his playing-time outlook, his poor form at the plate to begin the season could continue to cost him a couple starts per week. He's batting just .188 with two extra-base hits and a career-worst 37.7 percent strikeout rate over 53 plate appearances.

White (foot) is available off Atlanta's bench against Miami on Wednesday, Barrett Sallee of 680 The Fan Atlanta reports.

White has not appeared in a game since April 7 due to plantar fasciitis. He's progressed enough in his recovery to be available for Wednesday's game but could be in the starting lineup for Friday's series opener against the Phillies. White has gone 2-for-13 (.154) with two RBI to open the 2026 season.

Perez will start Friday's game against the Phillies, Mark Bowman of MLB.com reports.

Perez elected free agency Tuesday, returned to Atlanta on a minor-league pact Wednesday, and he's now set to rejoin the big-league rotation Friday. The 35-year-old lefty owns a 3.14 ERA and 0.91 WHIP through 14.1 innings on the season, and he'll match up against a Philadelphia offense that's posted just a .229 batting average (22nd in MLB) across its first 18 games.

Cole (elbow) will begin a rehab assignment at Double-A Somerset on Friday, Bryan Hoch of MLB.com reports.

Cole has built up to three innings (42 pitches) while pitching in sim games, and he's now been given the green light to begin playing in minor-league games. Because he's on the 15-day IL, the 35-year-old righty will be eligible to return at any moment, but the Yankees will presumably look to slowly build him up over the course of several rehab outings while he finishes up his recovery from Tommy John surgery.

The Rangers selected Quantrill's contract from Triple-A Round Rock on Wednesday, Kennedi Landry of MLB.com reports.

Quantrill has made three starts at Round Rock so far this year and owns a 5.14 ERA and 1.07 WHIP through 14 innings. The Rangers are short on bullpen arms after losing Chris Martin (biceps) and Luis Curvelo (shoulder) to the injured list Wednesday, so Quantrill could be tapped for long-relief duties while in the majors.

Yesavage (shoulder) gave up three earned runs on seven hits and one walk while striking out five batters across 4.1 innings during his rehab start at Triple-A Buffalo on Wednesday.

Although Yesavage was roughed up a bit, manager John Schneider said the 22-year-old righty "looked like himself" Wednesday while averaging 93.3 miles per hour with his fastball, per Arden Zwelling of Sportsnet.ca. He threw 71 pitches (42 strikes) in what is expected to be his final rehab start before coming off the injured list. Yesavage appears on track to make his season debut during next week's road series versus the Angels.

Early (1-0) picked up the win Wednesday, allowing one run on two hits and two walks over six innings in a 9-5 victory over the Twins. He struck out five.

The young southpaw delivered his first quality start of the season along with his first win, and the only blemish on his line was a first-inning solo shot by Austin Martin. Early tossed 52 of his 85 pitches for strikes, and he has yet to give up more than two runs in an outing in 2026. He'll take a 2.29 ERA, 1.27 WHIP and 20:10 K:BB through 19.2 innings into his next trip to the mound, which is scheduled to come at home early next week against the Yankees.

May (2-2) picked up the win in Wednesday's 5-3 victory over the Guardians, allowing one run on six hits and a walk over six innings. He struck out four.

The right-hander was far from dominant, managing a paltry two swinging strikes among his 91 pitches (59 total strikes), but May limited the damage in his second straight quality start and second straight win. It's a remarkable turnaround from his first two outings of 2026 -- in which he surrendered a combined 13 runs -- but his margin for error seems very thin without missing more bats. May will take a 6.98 ERA, 1.60 WHIP and 15:4 K:BB through 19.1 innings into his next start, which lines up to come on the road early next week in Miami.

Jansen worked around a hit to toss a scoreless inning of relief and earn the save in Wednesday's 2-1 win over the Royals. He struck out one.

Jansen recorded his second save in as many days, and he now has four this year in five opportunities. The veteran righty also has a strong 1.93 ERA, 0.86 WHIP and seven strikeouts across 4.2 innings so far. Jansen appears to be settling in with his new team, and the 38-year-old should remain a reliable fantasy option the rest of the way as long as he remains healthy in his 17th MLB season.

The Rangers transferred Bradford (elbow) to the 60-day injured list Wednesday.

Bradford has been working his way back from an internal brace procedure and made his first rehab start April 3, but his second outing has since been delayed, and his move to the 60-day IL suggests he isn't close to returning. He'll remain sidelined until at least late May, and he'll give up his place on the 40-man roster to help make room for Cal Quantrill and Gavin Collyer.

Thompson (1-0) retired all three batters faced in a scoreless ninth inning to record the win in Wednesday's 8-5 extra-inning victory over the Orioles.

Thompson induced groundouts and a flyout and has yet to allow a run over 11 appearances (7.2 innings). The submarining right-hander has not allowed a baserunner in his last six outings.

The Rangers selected Collyer's contract from Triple-A Round Rock on Wednesday, Kennedi Landry of MLB.com reports.

Collyer will come up from the minors to help fill the holes in Texas' bullpen left by Chris Martin (biceps) and Luis Curvelo (shoulder). The 24-year-old Collyer has started the Triple-A season strong, giving up just two runs over 6.2 innings while striking out 11 batters and walking two. He'll be making his MLB debut whenever he gets into a game.

The Rangers placed Curvelo on the 15-day injured list Wednesday with a right shoulder impingement, Kennedi Landry of MLB.com reports.

Curvelo threw just two pitches Tuesday before leaving the game with an injury, and he's now set to miss at least the next 15 days as well. With Chris Martin (biceps) also landing on the IL on Wednesday, Gavin Collyer and Cal Quantrill will come up from the minors to fill the openings in Texas' pitching staff.

The Rangers placed Martin on the 15-day injured list Wednesday with a bicep injury, Kennedi Landry of MLB.com reports.

Martin was pulled from his appearance Tuesday after throwing just five pitches in one-third of an inning, and he'll now be held out of action for the rest of the month after suffering a biceps injury. He'll be joined on the injured list by Luis Curvelo (shoulder), and the Rangers will bring up Gavin Collyer and Cal Quantrill from Triple-A Round Rock to round out the active roster.

Vientos is not in the Mets' starting lineup against the Dodgers on Wednesday.

Vientos has not recorded a hit over his last seven games, going 0-for-23 with eight strikeouts and a sacrifice fly over that span. He'll be on the bench for Wednesday's game while Brett Baty starts at first base and bats third.

Dodgers manager Dave Roberts told reporters that Ohtani will start on the mound against the Mets on Wednesday but will not serve as the team's designated hitter, Buster Olney of ESPN reports.

The decision to have Ohtani out of the lineup was tied to when he was hit by a David Peterson pitch during Monday's game against New York, per Fabian Ardaya of The Athletic. Ohtani has gone 0-for-7 with one run scored over his last two outings and will have the opportunity to focus solely on pitching during Wednesday's contest. Dalton Rushing will serve as the Dodgers' designated hitter and bat seventh while Kyle Tucker moves up to the leadoff spot.

Soler's suspension has been reduced to four games, and he will begin serving the ban during Wednesday's game against the Yankees, Rhett Bollinger of MLB.com reports.

Soler had initially received a seven-game ban for his involvement in a brawl during the Angels' 7-2 loss to Atlanta on April 7. After getting the suspension reduced, Soler will be eligible to return for Sunday's series finale against the Padres. The Angels will likely mix and match at designated hitter over the next four games while Soler is unavailable.

Baker started at first base and went 1-for-4 in Tuesday's 4-3 win over Baltimore.

Baker entered the starting nine after Ketel Marte (back) was scratched. That forced a lineup reshuffle with Ildemaro Vargas moving from first base to cover second and Baker getting his first start since being called up last week. Marte's injury is not considered serious, and Vargas could move back to first base for Wednesday afternoon's series finale.

Soler went 1-for-3 with a solo home run, two walks and two runs scored in Tuesday's 7-1 win over the Yankees.

After Mike Trout and Jo Adell both went deep off Ryan Weathers in the top of the first inning, Soler hit a solo shot of his own to make it back-to-back-to-back homers for the Angels. It was Soler's fifth long ball of the young season and his fourth in the last seven games. In that span, Soler owns a 1.185 OPS with 10 RBI, seven runs scored and a 4:7 BB:K across 31 trips to the plate.

Buxton went 4-for-5 with two home runs and four runs scored in Tuesday's 6-0 win over the Red Sox.

Buxton stayed hot at the plate, launching two homers that both traveled over 400 feet as part of a huge four-hit performance. His first came off Sonny Gray in the third inning on the first pitch of the frame, and he added another solo shot in the sixth. It was the 18th multi-homer game of Buxton's career and came one day after he hit his first long ball of the season. The center fielder now appears to be finding his power stroke, slashing .246/.306/.462 with three homers, four RBI and 15 runs scored on the year.