| Team Ranking | Overall | Rushing | Passing |
| Offense | 19th | 138.6 (6th) | 204.3 (25th) |
| Defense | 22nd | 145.8 (30th) | 217.1 (10th) |
| Date | Player | Pos. | Description |
| 2/15 | Terrence McGee | DB | Probable for start of training camp |
| 3/13 | Mike Caussin | TE | Questionable for start of training camp |
| 1/28 | Fred Jackson | RB | Probable for start of training camp |
| 5/30 | Lee Smith | TE | Questionable for start of training camp |
| 3/13 | Scott Chandler | TE | Questionable for start of training camp |
| Full injuries report | |||
| Date | Player | Pos. | Description |
| 6/14 | E.J. Manuel | QB | signed/draft choice, Four-year contract (fifth-year option) |
| 6/10 | Tarvaris Jackson | QB | cut |
| 6/05 | Greg Lloyd | LB | cut |
| 6/05 | Doug Legursky | C | signed/unrestricted free agent |
| 5/30 | DeMarco Sampson | WR | signed |
| Complete Bills Transactions | |||
| 2013 Draft | ||||
| Rnd | Sel | Player | Pos | School |
| 1 | 16 | Manuel, E. | QB | Florida State |
| 2 | 41 | Woods, R. | WR | Southern California |
| 2 | 46 | Alonso, K. | ILB | Oregon |
| 3 | 78 | Goodwin, M. | WR | Texas |
| 4 | 105 | Williams, D. | SS | Nevada |
| 5 | 143 | Meeks, J. | SS | Clemson |
| 6 | 177 | Hopkins, D. | K | Florida State |
| 7 | 222 | Gragg, C. | TE | Arkansas |
| Full Draft Tracker | ||||
| AFC East | |||||||
| Team | W | L | T | PF | PA | DIV | Streak |
| z-New England | 12 | 4 | 0 | 557 | 331 | 6-0 | Won 2 |
| Miami | 7 | 9 | 0 | 288 | 317 | 2-4 | Lost 1 |
| N.Y. Jets | 6 | 10 | 0 | 281 | 375 | 2-4 | Lost 3 |
| Buffalo | 6 | 10 | 0 | 344 | 435 | 2-4 | Won 1 |
| Complete Standings | |||||||
| 2013 Schedule | Buy Bills Tickets |
| Date | Opponent | Time/Result |
| Sep 8 | New England | 1:00 pm |
| Sep 15 | Carolina | 1:00 pm |
| Sep 22 | @N.Y. Jets | 4:25 pm |
| Sep 29 | Baltimore | 1:00 pm |
| Oct 3 | @Cleveland | 8:25 pm |
| Oct 13 | Cincinnati | 1:00 pm |
| Oct 20 | @Miami | 1:00 pm |
| Oct 27 | @New Orleans | 1:00 pm |
| Nov 3 | Kansas City | 1:00 pm |
| Nov 10 | @Pittsburgh | 1:00 pm |
| Nov 17 | N.Y. Jets | 1:00 pm |
| Week 12 | BYE | |
| Dec 1 | Atlanta (Toronto, Ont.) | 4:05 pm |
| Dec 8 | @Tampa Bay | 1:00 pm |
| Dec 15 | @Jacksonville | 1:00 pm |
| Dec 22 | Miami | 1:00 pm |
| Dec 29 | @New England | 1:00 pm |
| All times are Eastern | ||
| Complete Schedules | ||
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| Current | Team | Previous |
| 31 | Bills · Trends | 31 |
| They better hope EJ Manuel is who they think he can be. If not, it's going to be another long couple of years for the Bills. | ||
| Complete Rankings | ||
