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Struggling teams meet at Gainbridge Fieldhouse on Wednesday evening as the Indiana Pacers host the Chicago Bulls in a clash between Central Division foes in dire need of a victory. Indiana is 1-9 in the last 10 games, falling to 25-34 overall, and Chicago is on a four-game losing streak with a 26-31 overall record. Myles Turner (back) is questionable for the Pacers. DeMar DeRozan (quad) and Lonzo Ball (knee) are out for the Bulls, with Alex Caruso (foot) listed as questionable.

Caesars Sportsbook lists Indiana as a 2.5-point favorite, and tip-off is scheduled for 7 p.m. ET. The total number of points Vegas thinks will be scored, or the over/under, is 231.5 in the latest Bulls vs. Pacers odds. Before you make any NBA predictions with the Pacers vs. Bulls match-up, you need to see the NBA predictions and betting advice from SportsLine's advanced computer model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past four-plus seasons. The model enters Week 18 of the 2022-23 NBA season on a stunning 55-29 roll on all top-rated NBA picks this season, returning nearly $2,200. Anyone following it has seen huge returns.

Now, the model has set its sights on Bulls vs. Pacers and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and betting lines for Pacers vs. Bulls:

  • Bulls vs. Pacers spread: Pacers -2.5
  • Bulls vs. Pacers over/under: 231.5 points
  • Bulls vs. Pacers money line: Pacers -140, Bulls +118
  • CHI: The Bulls are 12-15-1 against the spread in road games
  • IND: The Pacers are 18-13 against the spread in home games
  • Bulls vs. Pacers picks: See picks at SportsLine

Why the Bulls can cover

Chicago has a friendly offensive matchup against Indiana. The Pacers are No. 24 in the NBA in defensive efficiency, with the league's worst defensive rebound rate at 68.7%. Indiana is in the bottom five in 3-point defense (37.3%), and the Pacers are No. 25 in the NBA in free throw attempts allowed (25.5 per game). Chicago is in the top six in field goal percentage (48.8%) and free throw percentage (81.3%), and the Bulls commit a turnover on only 13.8% of offensive possessions.

On defense, the Bulls allow 111.8 points per 100 possessions, a top-eight mark in the NBA, and Chicago ranks in the top three in defensive rating since the start of 2023. The Bulls are in the top 10 in fast break points allowed, field goal percentage allowed, and free throw attempts allowed, with Chicago ranking in the top three in defensive rebound rate (74.1%) and second-chance points allowed (12.8 per game).

Why the Pacers can cover

Indiana is keyed by an exciting and dynamic offense, with Tyrese Haliburton in the middle of the attack. Haliburton is averaging 20.0 points and 10.1 assists per game, and he is shooting 39.8% from beyond the 3-point arc. Haliburton is also the engine of Indiana's transition game, with the Pacers leading the NBA with 18.7 fast break points per game. Indiana is sixth with 26.4 assists per game, and the Pacers shoot 79.3% at the free throw line, a top-10 figure. 

On defense, Indiana's approach is havoc-based, with the Pacers creating 15.7 turnovers per game. That ranks in the top five of the NBA, and Indiana is in the top eight in steals (8.0 per game) and blocked shots (5.8 per game). Chicago is dead-last in the NBA in 3-pointers per game (10.2) and below the league average in free throw attempts and assists per game.

How to make Pacers vs. Bulls picks

SportsLine's model is leaning Under on the point total, with just one player projected to score at least 21 points. The model also says one side of the spread hits in almost 70% of simulations. You can only see the model's pick at SportsLine.

So who wins Bulls vs. Pacers? And which side of the spread hits in almost 70% of simulations? Visit SportsLine now to see which side of the Pacers vs. Bulls spread you need to jump on Wednesday, all from the model that has crushed its NBA picks, and find out.