1. Pittsburgh Steelers at New England Patriots - Week 1
The Steelers will visit the defending Super Bowl champions on Sept. 10 to kick off the 2015 regular season. Will the Patriots be able to defend their title?
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2. Baltimore Ravens at Denver Broncos - Week 1
New Broncos coach Gary Kubiak gets his former employer to open the season at Mile High. All eyes will be on Peyton Manning and his arm strength against the Ravens.
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3. Patriots at Buffalo Bills - Week 2
Week 2 will see freshly hired Rex Ryan welcome some old friends in Tom Brady and Bill Belichick to Western New York. Ryan always has something up his sleeve for the Patriots; can his Bills pull off the upset?
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4. Seattle Seahawks at Green Bay Packers - Week 2
The Packers have been waiting all offseason to get revenge from the 2014 NFC Championship Game. That, along with the infamous "Fail Mary" means this game has classic written all over it.
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5. Detroit Lions at Seattle Seahawks - Week 4
Megatron versus the Legion of Boom on Monday Night Football. Where do we sign? The Lions could make an early statement pulling off a win in Seattle.
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6. Patriots at Dallas Cowboys - Week 5
Two of the most electric offenses in the league will face off Week 5. The Patriots lost a lot of names on the defensive side of the ball. Can New England stop the Cowboys potent offense?
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7. Patriots at Colts - Week 6
By Week 6 we'll already have seen rematches of both championship games from last season. This feels like the year Andrew Luck pushes the Colts past the AFC super powers.
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8. Seahawks at San Francisco 49ers - Week 7
Another year, another Thursday night bloodbath between the 49ers and Seahawks. The Seahawks remain an elite team in the NFC, but where do the Niners stand after a tumultuous offseason?
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9. New York Jets at Patriots - Week 7
One-year rental Darrelle Revis returns to Foxboro in Week 7 to take on his former team. Rex Ryan isn't the Jets' coach anymore, but these two teams still aren't necessarily fond of each other.
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10. Cincinnati Bengals at Steelers - Week 8
The AFC North clash between the Steelers and Bengals will have huge implications that'll be felt in December and January.
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11. Seahawks at Cowboys - Week 8
The Cowboys pulled off the rare feat of beating the Seahawks in Seattle last season. Now, the Super Bowl losers will look to deal a loss in Dallas this year.
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12. Green Bay Packers at Broncos - Week 8
Sit back and kick your feet up as you watch Aaron Rodgers and Peyton Manning duel it out in Denver. There might not be a better quarterback matchup this season.
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13. Colts at Carolina Panthers - Week 8
Former top picks will battle it out for supremacy when Andrew Luck and Cam Newton play in Week 8. Which quarterback is the future of the NFL?
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14. Broncos at Colts - Week 9
This could be the final time Peyton Manning slings it in Indianapolis. Expect a warm welcome, and then some hearty boos once the game starts.
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15. Philadelphia Eagles at Cowboys - Week 9
DeMarco Murray will make his first appearance in Dallas as an Eagle. The two top teams in the NFC East last season always put on a fun show.
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16. Bills at Jets - Week 10
Rex Ryan comes home to the Meadowlands after coaching the Jets for six seasons.
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17. Patriots at New York Giants - Week 10
The Patriots will seek retribution following heartbreaking losses to the Giants in two Super Bowls. How will Belichick game plan against phenom wide receiver Odell Beckham?
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18. Chicago Bears at Green Bay Packers - Week 12
Brett Favre will finally get his number retired by the Packers. It also happens to be on Thanksgiving night. What a lovely holiday treat.
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19. Patriots at Broncos - Week 12
We hope this won't be our last Tom Brady versus Peyton Manning showdown. There's always the playoffs.
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20. Cowboys at Packers - Week 14
The Packers eliminated the Cowboys last season after a controversial no-catch call with Dez Bryant. No doubt Bryant will be pumped up for this game, we'll see if he can hold on.
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21. Seahawks at Ravens - Week 14
The Seahawks and Ravens don't face each other often, which is too bad. So we'll enjoy this potential Super Bowl matchup on Sunday night.
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22. Houston Texans at Colts - Week 15
Andre Johnson facing his old team, the Texans? Yes. J.J. Watt versus Andrew Luck? Yes, please!
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23. Steelers at Ravens - Week 16
The Steelers-Ravens rivalry has been one of the best in the last decade. These two teams could decide the AFC North in Week 16.
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24. Seahawks at Arizona Cardinals - Week 17
The Week 17 battle between the Cardinals and Seahawks could have huge playoff implications in the last week of the regular season. Will the winner of this game be the NFC West champs?
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25. Ravens at Bengals - Week 17
Like the NFC West battle, this AFC North tilt could decide the division. Andy Dalton and the Bengals will look to finally push through in the playoffs.
