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0:38Is Brandon Aiyuk Disinterested In Continuing To Be A 49ers
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1:29How 49ers Should Proceed With Brandon Aiyuk
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1:4349ers Preparing to Move on from WR Brandon Aiyuk
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0:44Kyle Shanahan Indicates Brandon Aiyuk Will Miss Significant Time
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1:47Brandon Aiyuk (ACL) Not Expected to Return Until October
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3:50Are the Browns Truly In On Brandon Aiyuk or Brock Purdy?
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3:59Are the Browns Going to Trade for Brandon Aiyuk?
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1:5549ers One Win Away From Historic Home Playoff Run
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1:00Easiest Path: Win & Get The NFC 1-Seed
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1:33Game Pick: Panthers at Buccaneers
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1:16Game Pick: Seahawks at 49ers
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1:47How Can The Seahawks Slow Down Brock Purdy?
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9:39NFL Week 18 Game Preview: Seahawks at 49ers
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1:39NFL Week 18 Projections: Seahawks & 49ers Dueling for No. 1 Seed in NFC
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1:13NFL Week 18 Expert Pick: Seahawks or 49ers
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2:31NFL Week 18 Picks: Week 18 Parlay
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3:17NFL Week 18 Picks: Seahawks at 49ers
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2:59NFL Week 18 Picks: Seahawks at 49ers
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0:46Quick Look At Pete Prisco's NFL Power Rankings, Presented by Geico
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1:11Race for No.1 Seed In The NFC
Top Brandon Aiyuk News
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49ers' Brandon Aiyuk: Done for 2025
The 49ers placed Aiyuk (knee) on the reserve/left squad list Saturday, Matt Barrows of The Athletic reports.
The move means Aiyuk will not return for the rest of the season and will likely not be a part of the 49ers' plans from 2026 and beyond. Aiyuk has been recovering from ACL and MCL tears in his right knee that he sustained during the 2024 campaign, and it's unclear whether the 49ers will look to trade the 2020 first-rounder during the offseason or cut him from the roster outright.
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49ers' Brandon Aiyuk: Not ruled out from playing in 2025
San Francisco general manager John Lynch reiterated Tuesday that he's still "hopeful" Aiyuk (knee) will play at some point this season, though he acknowledged that he wasn't sure how realistic the wideout's return might be, Cam Inman of The San Jose Mercury News reports.
Lynch noted that Aiyuk is continuing to take part in rehab work for the surgery he underwent last October to address ACL and MCL tears in his right knee, but the 49ers have thus far declined to put out a target date for when the 27-year-old might be ready to practice. As David Lombardi of SFStandard.com suggests, the decision as to whether Aiyuk suits up in 2025 likely falls on the wideout's shoulders. While the 49ers would seemingly welcome him back if he's healthy enough to play, Aiyuk may not be as motivated to suit up after San Francisco voided approximately $26 million on his contract back in late July. Aiyuk is still on San Francisco's books through 2028, though the team will likely look to trade him this offseason if a suitor is willing to pick up most of his remaining salary. Releasing Aiyuk is another possibility, but the 49ers would incur a dead-cap charge of $29.585 million if he's cut outright without a post-June 1 designation.
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49ers' Brandon Aiyuk: Not practicing this week
Aiyuk (knee) won't return to practice this week, Matt Maiocco of NBC Sports Bay Area reports.
Aiyuk reportedly wants to sit out the rest of the season and then angle for his release rather than playing for the 49ers after they voided guarantees in his four-year extension. The team, meanwhile, is hoping to get Aiyuk back on the field at some point this season, though it presumably wouldn't be until late December or January. It's unclear if Aiyuk would be considered ready for practice if not for his displeasure with the 49ers.
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Player Bio
| HT/WT: 6-0, 200 lbs |
| Birthplace: Rocklin, CA |
| Age: 27 |
| School: Arizona St. |
| Experience: 6 |