The 49ers DST came into the season highly regarded, but has been a major disappointment. San Francisco is tied for 28th with 14 Fantasy points through two games.
When nose tackle Ian Williams broke his ankle against the Seahawks, Glenn Dorsey replaced him and the run defense suffered. Marshawn Lynch ended up running for 98 yards and scoring three touchdowns. Rookie safety Eric Reid, meanwhile, is dealing with a concussion.
Still, the 49ers are at home Sunday for their best matchup of the young season. Start them against Indianapolis and expect their most productive performance yet. Two of three CBSSports.com experts peg the 49ers DST as a top-8 play this week.