Bradham, 25, will be a free agent after the 2015 season and he is coming off a career high in tackles, sacks and interceptions during the 2014 season.
Jackson missed practice Friday because of an illness but is listed as questionable because of a nagging ankle injury. However, a source told ESPN he's expected to play on Sunday.
The following players have been deemed questionable by the Bills: DT Kyle Williams – knee
Bradham and Kyle Williams were doubtful to play on the team's final injury report, and the absence of both key defenders could cause problems against the Lions offense. Easley and Chris Williams had already been ruled out Friday.
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