Skip to Main Content
Content on this page may include affiliate links. If you click and sign up/place a wager, we may receive compensation at no cost to you.

Jaguars vs. 49ers Live updates Score, results, highlights, for Sunday's NFL game

The San Francisco 49ers have enjoyed the comforts of home their last two games, but now they must head out on the road. They will take on the Jacksonville Jaguars at 1 p.m. ET on Sunday at TIAA Bank Field. The 49ers should still be riding high after a big victory, while Jacksonville will be looking to regain their footing.

San Francisco took their contest against the Los Angeles Rams this past Monday by a conclusive 31-10 score. San Francisco's WR Deebo Samuel did his thing and punched in one rushing touchdown in addition to catching five passes for one TD and 97 yards.

Meanwhile, Jacksonville was within a late touchdown of stealing the win, but they took the "L" against the Indianapolis Colts 23-17. WR Jamal Agnew put forth a good effort for the losing side as he punched in one rushing touchdown. That touchdown -- a 66-yard rush in the first quarter -- was one of the highlights of the game.

San Francisco is the favorite in this one, with an expected 6.5-point margin of victory. Those who got lucky with them against the spread this past Monday might want to hold off on placing bets this time since the squad has yet to string together back-to-back wins against the spread.

The 49ers' victory brought them up to 4-5 while the Jaguars' loss pulled them down to 2-7. San Francisco is 1-2 after wins this year, and Jacksonville is 2-4 after losses.

Updates
(72)
See New Posts
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 9:40 PM
Nov. 21, 2021, 4:40 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:32 PM
Nov. 21, 2021, 4:32 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 9:30 PM
Nov. 21, 2021, 4:30 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:21 PM
Nov. 21, 2021, 4:21 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 9:20 PM
Nov. 21, 2021, 4:20 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:13 PM
Nov. 21, 2021, 4:13 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 9:11 PM
Nov. 21, 2021, 4:11 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:11 PM
Nov. 21, 2021, 4:11 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:10 PM
Nov. 21, 2021, 4:10 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:03 PM
Nov. 21, 2021, 4:03 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 9:01 PM
Nov. 21, 2021, 4:01 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:58 PM
Nov. 21, 2021, 3:58 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 8:54 PM
Nov. 21, 2021, 3:54 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 8:48 PM
Nov. 21, 2021, 3:48 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:48 PM
Nov. 21, 2021, 3:48 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 8:39 PM
Nov. 21, 2021, 3:39 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:33 PM
Nov. 21, 2021, 3:33 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 8:24 PM
Nov. 21, 2021, 3:24 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:22 PM
Nov. 21, 2021, 3:22 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:19 PM
Nov. 21, 2021, 3:19 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 8:11 PM
Nov. 21, 2021, 3:11 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 8:11 PM
Nov. 21, 2021, 3:11 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 7:50 PM
Nov. 21, 2021, 2:50 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 7:49 PM
Nov. 21, 2021, 2:49 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 7:36 PM
Nov. 21, 2021, 2:36 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 7:26 PM
Nov. 21, 2021, 2:26 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 7:22 PM
Nov. 21, 2021, 2:22 pm EST
 
Pinned
Link copied
@49ers via Twitter
November 21, 2021, 7:21 PM
Nov. 21, 2021, 2:21 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 7:21 PM
Nov. 21, 2021, 2:21 pm EST
 
Pinned
Link copied
@Jaguars via Twitter
November 21, 2021, 7:10 PM
Nov. 21, 2021, 2:10 pm EST
See More
default-cbs-image
Now Playing

Share Video

Link copied!
  • Image thumbnail
    0:22

    JUST IN: Colts to Bring in QB Philip Rivers for Workout

  • Image thumbnail
    1:51

    Jaguars Look To Extend AFC South Lead As Colts Deal With QB Woes

  • Image thumbnail
    0:52

    Ravens Playoff Hopes Down To 23%, Travel To Cincinnati For Week 15

  • Image thumbnail
    1:37

    Chiefs Begin Must-Win Stretch vs. Chargers

  • Image thumbnail
    1:38

    Broncos Host Packers In Midst Of 10-Game Win Streak

  • Image thumbnail
    1:16

    Patriots Look To Hold Off Another Late-Season Comeback From Bills

  • Image thumbnail
    1:54

    MNF: Pick to Win Eagles at Chargers

  • Image thumbnail
    1:55

    MNF: Chargers Defense Playing Lights Out at Home

  • Image thumbnail
    1:25

    MNF: Eagles Place Positivity Bunny in Locker Room

  • Image thumbnail
    1:26

    MNF: Jalen Carter Out After Double Shoulder Surgery

  • Image thumbnail
    1:58

    MNF: Justin Herbert Questionable After Hand Surgery

  • Image thumbnail
    1:52

    Panthers Tied With Buccaneers In NFC South With 4 Games Remaining

  • Image thumbnail
    1:45

    Lions Still Outside Of Playoff Picture After Win Over Cowboys

  • Image thumbnail
    1:45

    Chiefs Playoff Hopes Down To 9% After Loss To Texans

  • Image thumbnail
    1:58

    Ravens Fall Behind In AFC North Division Race With Tough Road Ahead

  • Image thumbnail
    1:42

    Colts Lose 3 Straight, Now Without Daniel Jones

  • Image thumbnail
    1:59

    Raiders Last Second Field Goal Attempt Causes Concern For Many

  • Image thumbnail
    1:54

    Where Was Sanders On 2-Point Attempt?

  • Image thumbnail
    1:07

    Rookie QB Showdown: Ward Gets Win But Shedeur Shines

  • Image thumbnail
    1:40

    Officially Time To Panic In Tampa?