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Russell Wilson and the Seattle Seahawks will try to bounce back from a two-game losing streak when they host the Arizona Cardinals on Thursday Night Football. Seattle remains one of the league's top  offensive teams, but they were unable to knock off the Buffalo Bills or Los Angeles Rams in two recent road games. The Seahawks do have the benefit of home-field advantage on Thursday, however, with the Cardinals forced to travel on a short week. Arizona and Seattle are both 6-3, with the Cardinals topping the Bills with a last-second touchdown between Kyler Murray and DeAndre Hopkins last week. 

Kickoff is at 8:20 p.m. ET. William Hill Sportsbook lists Seattle as a three-point home favorite, while the over-under, or total number of points expected to be scored, is 57 in the latest Cardinals vs. Seahawks odds. Before making any Seahawks vs. Cardinals picks or NFL predictions, check out what SportsLine's resident Arizona expert, Zack Cimini, has to say.

Cimini is a highly respected Las Vegas handicapper who's never afraid to buck conventional wisdom. He also has an uncanny feel for the tendencies of the Cardinals, going 10-3 in his last 13 spread picks for or against Arizona. Anyone who has followed his NFL picks is way up.

Now, Cimini has looked at Cardinals vs. Seahawks from every possible angle. You can head to SportsLine to see his picks. Here are the NFL odds from William Hill and trends for Seahawks vs. Cardinals:

  • Cardinals vs. Seahawks spread: Seahawks -3
  • Cardinals vs. Seahawks over-under: 57 points
  • Cardinals vs. Seahawks money line: Seahawks -160, Cardinals +140
  • AZ: Cardinals are 4-2 against the spread in NFC games
  • SEA: Over has hit in six of nine Seahawks games

Why the Cardinals can cover

Defensively, Buddha Baker is a legitimate standout, ranking in the top five with 58 solo tackles this season. Haason Reddick is a top-five player in tackles for loss (10), while Arizona has an elite cornerback in Patrick Peterson.

On the offensive side, Murray is at the center of everything for Arizona, as the former No. 1 overall pick is dynamic on the ground and through the air. Murray leads the NFL in averaging 6.9 yards per carry on the ground and is a top-10 quarterback in completion percentage (68.2) and avoiding pressure, being sacked on only 4.01 percent of dropbacks. Finally, Hopkins remains one of the NFL's elite wide receivers, landing in the top three of the league in both catches (67) and receiving yards (861).

Why the Seahawks can cover

The Seahawks have been opportunistic on defense, forcing 15 turnovers to help mitigate damage. Seattle ranks in the top five of the league in takeaways and interceptions (nine), with the Seahawks also taking away the running game. Arizona is highly explosive on the ground, but Seattle ranks fourth in the NFL in both rushing yards allowed (95.0 per game) and yards per carry allowed (3.7) this season.

Bobby Wagner ranks in the top five of the NFL with 87 tackles, and the Seahawks could be well-suited to slowing Arizona's dynamic rushing attack. Seattle could also have an advantage on special teams, with Jason Myers maintaining a perfect mark on field goals this season and Michael Dickson ranking second in the NFL in punting average at 50.3 yards per kick.

How to make Cardinals vs. Seahawks picks

Cimini has analyzed this matchup, and while he's leaning over on the total, he has discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing it here. 

So who wins Seahawks vs. Cardinals on Thursday Night Football? And what critical X-factor makes one side of the spread a must-back? Visit SportsLine right now to find out which side of the Seahawks vs. Cardinals spread you should be all over, all from the expert who's 10-3 on Arizona picks, and find out.