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AC Milan attempt to accomplish an impressive feat when they visit Napoli for the second leg of their 2022-23 UEFA Champions League quarterfinal tie on Tuesday. AC Milan is looking to become the first team since Lazio in 1994-95 to defeat Napoli three times in one season. The Rossoneri have already beaten the Blues twice this month, cruising to a 4-0 victory in Serie A on April 2 before posting a 1-0 triumph in the first leg of this matchup. Both teams are coming off draws in league play on Saturday.

Kickoff at Stadio Diego Armando Maradona is set for 3 p.m. ET on Paramount+. Napoli are the -123 favorites (risk $123 to win $100) in the latest Napoli vs. AC Milan odds from Caesars Sportsbook, while AC Milan are +350 underdogs. A 90-minute draw is priced at +250 and the over/under for total goals scored is 2.5. Before locking in any AC Milan vs. Napoli picks, you need to see the UEFA Champions League predictions from SportsLine's Martin Green.

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Since last year's World Cup, Green is 77-81-3 (+4.32 units) with his soccer picks, including a 12-8 record (+2.17) with his Champions League predictions.

Now, Green has broken down AC Milan vs. Napoli from every angle and just revealed his picks and predictions. You can head to SportsLine now to see Green's picks. Here are the betting lines and trends for Napoli vs. AC Milan:

  • Napoli vs. AC Milan money line: Napoli -123, AC Milan +350, Draw +250
  • Napoli vs. AC Milan over/under: 2.5 goals
  • Napoli vs. AC Milan spread: Napoli -0.5 (-125)
  • NAP: Napoli have scored at least three goals in six of their nine UCL matches
  • MIL: AC Milan have allowed fewer than two goals in 11 of their last 13 games across all competitions
  • Napoli vs. AC Milan picks: See picks at SportsLine

Why you should back Napoli

Defeating Napoli at home in the Champions League is a tall order as they're unbeaten in their last 12 matches on their own pitch and have won all four this season. They have outscored their opponents 14-3 in those contests, netting at least three goals each time out. Nine of the 14 goals came from the trio of midfielder Piotr Zielinski and forwards Victor Osimhen and Giovanni Simeone, who recorded three apiece.

Those three players, along with forward Giacomo Raspadori, share the team lead with four goals during UCL play. Simeone is expected to miss Tuesday's match with a thigh injury, but Osimhen should be back in the lineup after sitting out the first leg with a similar issue. The 24-year-old Osimhen, who came off the bench in Napoli's 0-0 draw with Hellas Verona in Serie A action on Saturday, is the top scorer in the league with 21 goals in 24 contests. See who to back at SportsLine. 

Why you should back AC Milan

History is on the side of the Rossoneri as they've gone on to win 38 of the 44 UEFA ties in which they were victorious in the first leg at home. Napoli currently are struggling offensively, and their problems very well could continue against a defense that has been superb of late. Since being blanked by Chelsea in back-to-back games during the group stage, AC Milan have posted a clean sheet in each of their five subsequent matches. The club also has allowed just one goal in its last three Serie A contests.

The Rossoneri have averaged two goals over their last five Champions League games and would like to produce at least that many on Tuesday against a Napoli side that is tied for first in the UCL with 25 goals. French striker Olivier Giroud is Milan's top scorer in the competition with four goals and Belgian winger Alexis Saelemaekers (two) is the only other player on the club who has converted more than once. Portuguese forward Rafael Leao, who leads AC Milan in Serie A with 10 goals, has netted one in the UCL but recorded a brace against Napoli on Apr. 2. See who to back at SportsLine. 

How to make AC Milan vs. Napoli picks

Green has broken down the Champions League match from every angle. He is leaning Under on the goal total and has locked in a pair of confident best bets, one of which offers a plus-money payout, while offering a full breakdown of this matchup. You can only see his Champions League picks and analysis at SportsLine.

So who wins Napoli vs. AC Milan on Tuesday? And where does all the betting value lie? Visit SportsLine now to see which wagers in AC Milan vs. Napoli have all the value, all from the soccer expert who is on a 12-8 roll on Champions League picks, and find out.