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Just eight teams remain alive in the 2022 MLB playoffs, and on Tuesday all four Division Series begin. The day starts with the Braves and Phillies from Atlanta. They will be followed by the Astros versus the Mariners in Houston, and the Yankees hosting the Guardians in the Bronx. The day ends with two NL West rivals -- the Dodgers and Padres -- squaring off at Dodger Stadium in Los Angeles. Julio Urias (17-7, 2.16 ERA) will take the mound for Los Angeles against San Diego's Mike Clevinger.

Los Angeles is a -235 favorite in the latest Dodgers vs. Padres odds from Caesars Sportsbook, while San Diego is a +192 underdog. The over/under for runs scored is 7. Each series is a best-of-five, with the winners advancing to the league championship series. Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it enters the divisional round on a 20-11 roll on top-rated MLB money-line picks, returning more than $600. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen huge returns.

Now, the model has locked in four confident MLB best bets for Tuesday. If you successfully parlay the picks, you'd be looking at a payout of well over 16-1. You can only see the model's MLB picks at SportsLine. 

Top MLB playoff picks for Tuesday

The model, which ran 10,000 simulations on each of Tuesday's Division Series games, likes Cleveland (-130) to cover the +1.5 run line against New York. The Guardians enter the series on a high after sweeping Tampa Bay in their American League Wild Card Series. They are 15-3 in their last 18 games, while the Yankees are just 5-5 in their last 10.

Cleveland has arguably the hottest bullpen left in the playoffs. Led by dominant closer Emmanuel Clase, the Guardians had MLB's best bullpen ERA after the All-Star break. Cleveland's relief power was on full display in the Wild Card Series, pitching 10.1 scoreless innings while striking out 13 and walking just three across two games against Tampa Bay. See who else to back right here.

How to make MLB picks and parlays for Tuesday

The model also locked in three other best bets for Tuesday, including one on a big money line underdog. You can see the model's MLB Tuesday best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of well over 16-1? And what big money line underdog does the model like on Tuesday? Visit SportsLine now to see the MLB best bets from an advanced model that is on a 20-11 run on top-rated money-line picks.