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The Philadelphia 76ers will take on the Los Angeles Clippers at 10:30 p.m. ET on Friday at Crypto.com Arena. Los Angeles is 36-38 overall and 20-15 at home, while Philadelphia is 45-27 overall and 24-11 on the road. The Clippers pulled off a 102-101 upset as 7.5-point underdogs when these teams met in January. 

Philadelphia is favored by five points in the latest Clippers vs. 76ers odds from Caesars Sportsbook, while the over-under is set at 218. Before entering any 76ers vs. Clippers picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 22 of the 2021-22 NBA season on a stunning 79-49 roll on all top-rated NBA picks, returning over $2,400. Anyone following it has seen huge returns.

Now, the model has set its sights on Clippers vs. 76ers. You can head to SportsLine to see its picks. Here are several NBA betting lines for Sixers vs. Clippers:

  • Clippers vs. 76ers spread: Clippers +5
  • Clippers vs. 76ers over-under: 218 points

What you need to know about the Clippers

Los Angeles will be looking to snap a four-game losing streak on Friday night. The Clippers are coming off consecutive double-digit road losses at Utah and Denver. They will bring some confidence into this matchup though, as they erased a 24-point deficit in the second half of the first meeting between these teams. 

Los Angeles has been battling injuries this season, as star players Kawhi Leonard and Paul George are both sidelined. Also out is Norman Powell (foot) while Robert Covington is questionable with a hand injury. Veteran point guard Reggie Jackson is the active scoring leader, averaging 16.9 points and 4.8 assists per game. The Clippers have failed to cover the spread in each of their last five games. 

What you need to know about the 76ers

Philadelphia has won four of its last five games, including a 126-121 win over the Lakers on Wednesday. The 76ers have been able to stay in Los Angeles without any additional traveling before this game at Crypto.com Arena. Joel Embiid poured in 30 points and James Harden added 24 points in the win over the Lakers on Wednesday. 

Harden scored 39 points and dished out 15 assists against the Clippers in December when he was still with Brooklyn. Embiid is the second-leading scorer in the NBA, averaging 29.8 points per game. Philadelphia has covered the spread in nine of its last 12 games against the Clippers, including four of its last five road games. 

How to make Clippers vs. 76ers picks

The model has simulated Clippers vs. 76ers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You can only see the pick at SportsLine.

So who wins 76ers vs. Clippers? And which side covers almost 70 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its NBA picks.