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The Cleveland Cavaliers will take on the Houston Rockets at 8 p.m. ET on Wednesday at the Toyota Center. Houston is 14-36 overall and 7-16 at home, while the Cavaliers are 31-20 overall and 15-11 on the road. Cleveland has won nine of its last 11 games, but it will be without star point guard Darius Garland (back) on Wednesday night

Cleveland is favored by six points in the latest Rockets vs. Cavaliers odds from Caesars Sportsbook, while the over-under is set at 218.5. Before entering any Cavaliers vs. Rockets picks, you'll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 16 of the 2021-22 NBA season on a stunning 62-32 roll on all top-rated NBA picks, returning over $2,500. Anyone following it has seen huge returns.

Now, the model has set its sights on Rockets vs. Cavaliers. You can head to SportsLine to see its picks. Here are several NBA betting lines for Rockets vs. Cavaliers:

  • Rockets vs. Cavaliers spread: Rockets +6
  • Rockets vs. Cavaliers over-under: 218.5 points

What you need to know about the Rockets

Houston is now on an 11-game home losing streak following its 122-108 loss to Golden State on Monday. The Rockets were unable to overcome 21 fourth-quarter points from Warriors guard Stephen Curry. They also turned the ball over eight times in the third quarter, which has been a disturbing trend for a Houston team that ranks last in the NBA in turnovers per game (16.9). 

Center Christian Wood leads Houston with 17.7 points per game and is completing his double-double average with 10.4 rebounds. He has five teammates also scoring in double figures, headlined by Eric Gordon's 14.3 points per game. The Rockets have won 11 of their last 13 home games against Cleveland. 

What you need to know about the Cavaliers

Cleveland has now won nine of its last 11 games after picking up a 93-90 win over New Orleans on Monday. The Cavaliers had to scramble to replace Garland, who will remain sidelined with a back injury on Wednesday. Garland leads the team in scoring (19.8 points) and assists (8.2). 

The Cavaliers are already without forward Lauri Markkanen (ankle), who averages 13.6 points and 5.3 rebounds. Fortunately for Cleveland, its defense ranks third in the NBA in efficiency. In addition, the Cavaliers have covered the spread in five of their last six games against Houston. 

How to make Cavaliers vs. Rockets picks

The model has simulated Rockets vs. Cavaliers 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Cavaliers vs. Rockets? And which side of the spread covers over 50 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its NBA picks.