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The San Antonio Spurs (31-45) host the Portland Trail Blazers (27-49) at 8:30 p.m. ET on Friday, April 1 at AT&T Center in San Antonio. The Spurs saw their four-game winning streak snapped in a hard-fought 112-111 loss to the Memphis Grizzlies on Wednesday night, while the Trail Blazers' losing streak was extended to five games with their 117-107 loss to the New Orleans Pelicans on Mar. 30. The Spurs are 14-24 at home, while Portland is 10-26 on the road. 

The Spurs are favored by 15 points in the latest Spurs vs. Trail Blazers odds from Caesars Sportsbook, and the over-under is set at 230.5. Before making any Trail Blazers vs. Spurs picks, you need to see the NBA predictions and betting advice from the red-hot computer simulation model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 24 of the 2021-22 NBA season on a stunning 83-51 roll on all top-rated NBA picks, returning over $2,600. Anyone following it has seen huge returns.

Now, the model has set its sights on Spurs vs. Trail Blazers, and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and  betting lines for Spurs vs. Trail Blazers:

  • Spurs vs. Trail Blazers spread: Spurs -15
  • Spurs vs. Trail Blazers over-under: 230 points

What you need to know about the Spurs

San Antonio was just a bucket short of a win on Wednesday and fell 112-111 to the Memphis Grizzlies. Despite the defeat, San Antonio got a solid performance out of point guard Dejounte Murray, who shot 6-for-9 from beyond the arc and finished with a double-double on 33 points and 13 rebounds.

Murray had a breakout year in 2021-22, developing into an All-Star caliber player for San Antonio. The 6-foot-4 point guard is averaging 21.2 points, 9.3 assists, and 8.4 rebounds per game, and will be a matchup nightmare for Portland. The Spurs are 37-37-1 against the spread in 2021-22. 

What you need to know about the Trail Blazers

Meanwhile, Portland came up short against the New Orleans Pelicans on Wednesday, falling 117-107. The losing side was boosted by center Drew Eubanks, who had 21 points along with nine boards.

The Trail Blazers are stumbling into the matchup with the fourth most fouls per game in the league, having accrued 20.9 on average, which could be problematic given their depth issues that stem from their laundry list of injured and unavailable players. Portland has only won twice in its last 17 tries, and is 29-45-1 against the spread in 2021-22. 

How to make Trail Blazers vs. Spurs picks

The model has simulated Spurs vs. Trail Blazers 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You can only see the model's Blazers vs. Spurs pick at SportsLine.

So who wins Spurs vs. Trail Blazers? And which side of the spread hits almost 70 percent of the time? Visit SportsLine now to see which side of the Blazers vs. Spurs spread you need to jump on Friday, all from the model that has crushed its NBA picks, and find out.