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The San Francisco 49ers will try to return to the Super Bowl for the first time since 2019 when they take on the Detroit Lions in the 2024 NFC Championship Game on Sunday. The 49ers (12-5), who won the NFC West for the third time in five years, last won a Super Bowl in 1994. The Lions (12-5), who are seeking their first Super Bowl appearance, are making just their second NFC Championship Game appearance. The Lions are coming off their first division crown since 1993.

Kickoff is at 6:30 p.m. ET from Levi's Stadium in Santa Clara, Calif. San Francisco is a 7.5-point favorite in the latest Lions vs. 49ers odds, per SportsLine consensus. The over/under for total points scored is 51.5. Before you make any 49ers vs. Lions picks, you need to see what proven SportsLine NFL expert Micah Roberts has to say, considering his mastery of picks involving the 49ers.

Roberts has worked in the Las Vegas sportsbook industry for 20-plus years, including a 13-year run as Station Casinos' book director. He is 18-12-2 over his last 32 NFL picks, for a profit of $458. Additionally, Roberts is an astounding 21-5 (+1550) on his last 26 against the spread picks involving the 49ers. Anyone who has followed him is way up

Now, Roberts has broken down Lions vs. 49ers and just revealed his picks and predictions. You can visit SportsLine now to see his picks. Here are several NFL odds and betting trends for 49ers vs. Lions:

  • 49ers vs. Lions point spread: 49ers -7.5
  • 49ers vs. Lions over/under: 51.5 points
  • 49ers vs. Lions money line: 49ers -351, Lions +277
  • DET: Lions are a league-best 13-6 against the spread this season
  • SF: 49ers are 5-1 against the spread in their last six home playoff games
  • 49ers vs. Lions picks: See picks at SportsLine
  • 49ers vs. Lions live stream: fubo (try for free)

Why 49ers can cover

Quarterback Brock Purdy leads the San Francisco offense. During the regular season, Purdy completed 308 of 444 passes (69.4%) for 4,280 yards and 31 touchdowns with just 11 interceptions. He had a rating of 113, and also rushed for two touchdowns. He surpassed 300 yards passing five times, and was solid in the divisional round win over Green Bay last week, completing 23 of 39 passes for 252 yards and a score.

Running back Christian McCaffrey also has been a force on offense. During the regular season, he led the 49ers with 1,459 yards rushing on 272 carries (5.4 average) and 14 touchdowns. He also caught 67 passes for 564 yards (8.4 average) and seven touchdowns. He had four explosive plays of 20 yards or more, including a season-long 41-yarder. Against Green Bay last week, he carried 17 times for 98 yards (5.8 average) and two TDs. See which team to pick here.

Why Lions can cover

Quarterback Jared Goff is looking for his third game in a row with 275 or more passing yards and a 100-plus rating. He is aiming for his fifth playoff game in a row with a touchdown pass and no interceptions. He ranked second in passing yards (4,575) and fourth in touchdown passes (30) during the regular season. He passed for 338 yards and three touchdowns in his last regular-season meeting against the 49ers on Sept. 12, 2021. He has two or more touchdown passes in each of his four career starts at San Francisco.

Wide receiver Amon-Ra St. Brown had eight catches for 77 yards and his first career postseason TD last week. He can become the first player with seven or more catches in his first three career playoff games since 2018 (Michael Thomas). He was second in the NFL with a career-high 119 catches and was third with a career-high 1,515 receiving yards. He also had a career-high 10 receiving touchdowns this season. See which team to pick here.

How to make 49ers vs. Lions picks

Roberts has analyzed Lions vs. 49ers from every angle and is leaning Over the point total, but he has also discovered a critical X-factor that has him jumping all over one side of the spread. He's sharing what it is, and which side to back, only at SportsLine.

Who wins Lions vs. 49ers in Sunday's 2024 NFC Championship Game, and which critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the Lions vs. 49ers spread hits hard, all from the expert who is 21-5 on picks involving San Francisco, and find out.