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Villarreal is playing for the UEFA Europa League title for the first time, and it has exactly the right manager for the task. Unai Emery, who is in his first season with El Submarino Amarillo, guided Sevilla to three straight championships from 2014-16 and led Arsenal to the final in 2019 before falling to Chelsea. Emery hopes to bring Villarreal its first crown when it takes on Manchester United on Wednesday in the 2021 UEFA Europa League final. The Spanish side has yet to lose in the competition, registering 12 victories and a pair of draws en route to the title match.  

Kickoff from Gdansk Stadium in Gdansk, Poland is scheduled for 3 p.m. ET and can be streamed on Paramount+. The latest Manchester United vs. Villarreal odds from William Hill Sportsbook list Manchester United as 0.5-goal and -110 money-line favorite (risk $110 to win $100), while the over-under for total goals scored is 2.5. Before locking in any Villarreal vs. Manchester United picks, be sure to see the UEFA Europa League predictions and betting advice from SportsLine's Martin Green. 

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper. Since then, his European soccer picks have been spot-on. Green has generated almost $19,000 for $100 bettors since the 2017-18 season.

Now, he has set his sights on Manchester United vs. Villarreal. You can visit SportsLine now to see his picks. Here are several odds and trends for Villarreal vs. Manchester United:

  • Manchester United vs. Villarreal spread: Manchester United -0.5
  • Manchester United vs. Villarreal over-under: 2.5 goals
  • Manchester United vs. Villarreal money line: Manchester United -110, Villarreal +340, Draw +230
  • MU: The Red Devils have scored at least once in 16 straight knockout-phase matches outside of England
  • VIL: Villarreal is unbeaten in its last 12 Europa League games outside of Spain (seven wins, five draws)

Top Manchester United vs. Villarreal predictions 

Green is leaning over 2.5 goals in Wednesday's showdown between Manchester United and Villarreal. The Red Devils have four players with double-digit goal totals across all competitions this season, with Bruno Fernandes (28) leading the way. The 26-year-old Portuguese midfielder has netted four goals in his last six matches, including two against Roma in the first leg of the semifinals. Mason Greenwood has recorded eight of his 12 goals over his last 13 contests, while Edinson Cavani has scored nine times in his last 10 games.

Fernandes and Cavani (five each) have combined to register 10 of Manchester United's 18 goals during Europa League play, while Gerard Moreno and Paco Alcacer have scored six goals apiece for Villarreal. The 29-year-old Moreno finished the La Liga season tied for second with 23 goals after converting in three of his final four contests. Alcacer posted a pair of two-goal performances during the group stage and has recorded half of his 12 goals this campaign in Europa League action, which is one of the reasons Green is leaning toward the over on Wednesday.

How to make Europa League picks for Villarreal vs. Manchester United 

Green has taken a close look at Wednesday's matchup and locked in his best bets and analysis, which includes a strong money-line pick and a prop that returns plus-money. You can only get those picks at SportsLine.

So who wins Villarreal vs. Manchester United? And where does all the betting value lie? Visit SportsLine now to find out which side to back, all from the European soccer expert who's up almost $19k.