Syracuse vs. Clemson odds, line: 2021 college basketball picks, Mar. 3 predictions from proven model

The SportsLine projection model has a pick for the clash between Clemson and Syracuse. Here are the results

By Scout Staff

Mar 3, 2021 at 1:04 pm ET • 2 min read

USATSI

The Clemson Tigers and the Syracuse Orange are set to square off in an ACC matchup at 5 p.m. ET on Wednesday at the Carrier Dome. Syracuse is 14-8 overall and 12-1 at home, while the Tigers are 15-5 overall and 2-4 on the road. The Tigers have won six of the last 10 head-to-head matchups between these two teams.

Clemson is 10-9-1 against the number so far this season, while Syracuse is 9-13. The Orange are favored by two-points in the latest Syracuse vs. Clemson odds from William Hill Sportsbook, and the over-under is set at 135.5. Before entering any Clemson vs. Syracuse picks, you'll want to see the college basketball predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of over $2,600 for $100 players on its top-rated college basketball picks against the spread. It has also returned over $500 on all top-rated college basketball picks this season. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Syracuse vs. Clemson. You can head to SportsLine to see its picks. Here are several college basketball odds for Syracuse vs. Clemson:

Syracuse vs. Clemson spread: Syracuse -2
Syracuse vs. Clemson over-under: 135.5 points
Syracuse vs. Clemson money line: Syracuse -130, Clemson +110

What you need to know about Syracuse

The North Carolina Tar Heels have been playing better basketball of late and have played themselves into NCAA Tournament consideration but on Monday Syracuse proved too difficult a challenge. The Orange had just enough and edged out UNC 72-70. Syracuse's success was spearheaded by the efforts of guard Buddy Boeheim, who shot 6-for-13 from beyond the arc and finished with 26 points, and forward Quincy Guerrier, who had 18 points along with six boards.

Syracuse is now firmly back on the bubble but could certainly stand to add a victory on Wednesday against a Clemson squad that appears to have its ticket punched. Syracuse shot just 30 percent from the floor in the programs' previous meeting this season and creating higher-quality shot opportunities will be critical on Wednesday.

What you need to know about Clemson

Meanwhile, the Tigers beat the Miami (Fla.) Hurricanes 66-58 this past Saturday. Among those leading the charge for Clemson was guard Al-Amir Dawes, who had 19 points. Senior forward Aamir Simms also had 19 points and six rebounds in the win and he's the only Clemson player averaging double-figures (13.6 points per game) in scoring so far this season.

Clemson didn't have too much trouble with Syracuse at home in the teams' previous meeting in February as they won 78-61. The rematch might be a little tougher for Clemson since the team won't have home-court advantage.

How to make Syracuse vs. Clemson picks

The model has simulated Syracuse vs. Clemson 10,000 times and the results are in. We can tell you that the model is leaning over, and it's also generated a point-spread pick that is hitting in nearly 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Syracuse vs. Clemson? And which side of the spread hits in nearly 60 percent of simulations? Visit SportsLine right now to see which side of the Clemson vs. Syracuse spread you need to jump on, all from the computer model that has crushed its college basketball picks.