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The Texas A&M Aggies will take on the Colorado Buffaloes at 3:30 p.m. ET on Saturday at Mile High Stadium. Both programs are coming off strong seasons in 2020 with Texas A&M going 9-1 while Colorado went 4-2 in Karl Dorrell's first season as head coach, and both programs are off to 1-0 starts this year. The Aggies are coming off a 41-10 drubbing of Kent State while the Buffaloes beat Northern Colorado 35-7 in their opener.

This will be the 10th meeting all-time between these programs with Colorado holding a 6-3 edge in the series, but the teams haven't met since 2009. The Aggies are favored by 17 points in the latest Texas A&M vs. Colorado odds from Caesars Sportsbook, and the over-under is set at 50. Before entering any Colorado vs. Texas A&M picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 2 of the 2021 season on a 63-45 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Colorado vs. Texas A&M. You can head to SportsLine to see its picks. Here are several college football odds for Texas A&M vs. Colorado:

  • Texas A&M vs. Colorado spread: Texas A&M -17
  • Texas A&M vs. Colorado over-under: 50 points

What you need to know about Colorado

The Buffaloes made easy work of the Northern Colorado Bears on Friday and carried off a 35-7 win. RB Jarek Broussard was the offensive standout of the matchup for Colorado, punching in one rushing touchdown. The Buffaloes rushed for 281 total yards in the win with six different players carrying the ball and four different players scoring touchdowns.

Quarterback Brendon Lewis wasn't tested much in the opener, completing 10 of 15 passes for 102 yards and a touchdown while adding 44 yards on the ground. However, he'll be carrying a much larger burden against the Aggies after Texas A&M forced two turnovers and recorded five sacks last week.

What you need to know about Texas A&M

Meanwhile, when you finish with 259 more yards than your opponent like A&M did on Saturday, a favorable outcome is almost sure to follow. The Aggies blew past the Kent State Golden Flashes 41-10. The contest was all but wrapped up at the end of the third, by which point A&M had established a 27-3 advantage. 

They can attribute much of their success to RB Devon Achane, who rushed for two TDs and 124 yards on 12 carries. One of the most memorable plays of the game was Achane's 63-yard touchdown rush in the third quarter. Isaiah Spiller also topped the 100-yard mark with 113 yards on the ground and that pair should continue to form a dynamic 1-2 punch in the backfield.

How to make Texas A&M vs. Colorado picks

The model has simulated Colorado vs. Texas A&M 10,000 times and the results are in. The model is leaning over on the total and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Texas A&M vs. Colorado? And which side of the spread hits over 50 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.