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The Cleveland Cavaliers and the Detroit Pistons will face off in a Central Division clash at 7 p.m. ET on Friday at Little Caesars Arena. Detroit is 17-40 overall and 10-16 at home, while the Cavaliers are 20-36 overall and 9-20 on the road. The Cavaliers have won the last four games between the teams. 

Cleveland is favored by three points in the latest Pistons vs. Cavaliers odds from William Hill Sportsbook, and the over-under is set at 213. Before entering any Cavaliers vs. Pistons picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times, and it has returned over $9,100 in profit on its top-rated NBA picks over the past two-plus seasons. The model is up over $1,100 on its top-rated picks this season, and dating back to last year, it entered Week 17 of the 2020-21 NBA schedule on a stunning 95-59 roll on top-rated NBA picks against the spread. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Pistons vs. Cavs. You can head to SportsLine to see its picks. Here are several NBA betting lines for Cavs vs. Pistons:

  • Pistons vs. Cavaliers spread: Pistons +3
  • Pistons vs. Cavaliers over-under: 213 points
  • Pistons vs. Cavaliers money line: Cleveland -150, Detroit +130  

What you need to know about the Pistons

The Pistons were thumped by the Washington Wizards on Saturday, 121-100. Isaiah Stewart posted a double-double on 19 points and 12 rebounds. Detroit has lost four of its past five games. The Pistons have the worst record in the Eastern Conference, one game behind the Magic for the No. 14 spot. 

The Pistons have let their opponents to shoot 47.8 percent from the floor, the fifth highest shooting percentage allowed in the league, Jerami Grant (quadriceps), Dennis Smith Jr. (knee), Cory Joseph (illness), Rodney McGruder (elbow) and Sekou Doumbouya (concussion) are out for Monday's game. Wayne Ellington and Mason Plumlee will be rested. 

What you need to know about the Cavaliers

Meanwhile, the Cavaliers lost to the Chicago Bulls this past Saturday, 106-96. Darius Garland dropped a double-double on 22 points and 12 assists. Cleveland is three games behind the No. 10 spot in the Eastern Conference. The Cavaliers have lost four of their past five games. 

Cleveland has let its opponents to shoot 48 percent, which is the third highest shooting percentage allowed in the league. Dylan Windler (knee) and Larry Nance Jr. (personal) are out for Monday's game. 

How to make Cavaliers vs. Pistons picks

The model has simulated Pistons vs. Cavaliers 10,000 times and the results are in. It is leaning under on the total, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You can only see the pick at SportsLine.

So who wins Pistons vs. Cavaliers? And which side of the spread hits in almost 70 percent of simulations? Visit SportsLine now to see which side of the Pistons vs. Cavaliers spread to jump on Monday, all from the model that is on an incredible 95-59 roll.