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The Memphis Grizzlies look to continue their success against Eastern Conference opponents when they take on the host New York Knicks in NBA action on Friday. The Grizzlies (26-23), who are 14-9 on the road, have been dominant, going 14-6 against the East. The Knicks (25-27), who are 7-10 against Western Conference foes, have been tough to beat at home, going 14-10 on their home court. Memphis, however, has won two in a row at New York and five of the last seven there.

The game from Madison Square Garden in New York is scheduled for 7:30 p.m. ET. The Grizzlies are averaging 112.5 points per game, while the Knicks average 104.9. Memphis is a one-point favorite in the latest Grizzlies vs. Knicks odds from William Hill Sportsbook, while the over-under for total points scored is set at 215.5. Before finalizing any Knicks vs. Grizzlies picks, be sure to see the NBA predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every NBA game 10,000 times, and it has returned almost $8,900 in profit on its top-rated NBA picks over the past two-plus seasons. The model is up almost $900 on its top-rated picks this season, and dating back to last year, it entered Week 16 of the 2020-21 NBA schedule on a stunning 93-59 roll on top-rated NBA picks against the spread. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Knicks vs. Grizzlies. You can head to SportsLine to see its picks. Now, here are several NBA odds and betting trends for Grizzlies vs. Knicks:

  • Grizzlies vs. Knicks spread: Grizzlies -1
  • Grizzlies vs. Knicks over-under: 215.5 points
  • Grizzlies vs. Knicks money line: Grizzlies -120, Knicks +100
  • MEM: Is 4-0 against the spread in its last four road games
  • NY: Is 4-1-1 ATS in its last six games against a team with a winning straight-up record

Why the Grizzlies can cover

Veteran center Jonas Valanciunas has been dominant and is averaging 16.3 points, a career-high 12.4 rebounds and 1.8 assists in 27.5 minutes per game. He is on pace to set the single-season franchise record in rebounds per game, eclipsing the record of 12.2 by Zach Randolph in 2010-11. He ranks third in the league in rebounding average. Valanciunas has scored in double figures 40 times, including 13 games with at least 20 points and one game with at least 30. He has grabbed double-digit rebounds 37 times, including two games with at least 20 rebounds. He has posted 36 double-doubles.

Forward Kyle Anderson is one of seven Memphis players averaging in double figures. He is averaging 12.6 points, 5.9 rebounds, 3.5 assists and 1.2 steals per game, connecting on 47.8 percent of his field goals, including 36.7 percent from 3-point range, and 75.8 percent of his free throws. He has made a career-high 65 3-pointers this season. Anderson has reached double figures 31 times, including five games with at least 20 points. He has grabbed double-digit rebounds four times, and has posted three double-doubles.

Why the Knicks can cover

Despite that, Memphis isn't a lock to cover the Grizzlies vs. Knicks spread. That's because New York is much improved over last season's 21-45 team. Leading the way is power forward Julius Randle, who is averaging 22.9 points, 10.7 rebounds, six assists and 0.9 steals per game in 51 games, all starts. He recorded a triple-double with 19 points, 15 rebounds and 12 assists on Monday at Brooklyn and followed that up with a 22-point, nine-rebound effort on Wednesday at Boston. 

Shooting guard RJ Barrett is also a big part of New York's success and is averaging 17.5 points, 5.9 rebounds and three assists per game. Barrett is coming off a 29-point, five-rebound performance at Boston. He has led the team in scoring eight times and has registered 23 20-point performances and one 30-plus effort. He has posted four double-doubles. He scored a season-high 44 points against Oklahoma City on Jan. 8.

How to make Grizzlies vs. Knicks picks

SportsLine's model is leaning under on the total, projecting the teams to combine for 215 points. The model also says one side of the spread hits well over 50 percent of the time. You can get that pick at SportsLine.

So who wins Grizzlies vs. Knicks? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that is on a 93-59 roll on NBA picks.