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USATSI

NFL Week 7 comes to a close with a matchup between the Minnesota Vikings and San Francisco 49ers on Monday Night Football. Kickoff at U.S. Bank Stadium in Minneapolis is at 8:15 p.m. ET. Perennial Pro Bowl wide receivers Justin Jefferson (hamstring, IR) and Deebo Samuel (shoulder) are both out and will be absent from the NFL DFS player pool. All-Pro running back Christian McCaffrey will play through an oblique injury, and will be the highest-priced player on the MNF DFS slate. Should McCaffrey be a part of your NFL DFS stack and NFL DFS lineups? Before making any NFL DFS picks for Vikings vs. 49ers on sites like DraftKings and FanDuel, be sure to check out the NFL DFS lineup advice, strategy and player stacks from SportsLine NFL daily Fantasy expert Jimmie Kaylor. 

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for over a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

Kaylor hit on epic NFL DFS picks all season in 2022. He was all over Travis Kelce's four-touchdown performance against the Raiders on Monday Night Football, Kirk Cousins' 460-yard, four-TD performance on Thanksgiving Day, and T.J. Hockenson's 13 catches for 109 yards and two touchdowns in Week 15.

This year, Kaylor has been all over players like Justin Jefferson (11-159), D'Andre Swift (175-1), DeVonta Smith (4-132-1), T.J. Hockenson (7-66-2), D.J. Moore (8-230-3), David Montgomery (121-3), Ja'Marr Chase (12-141), and Alvin Kamara (12-91, 76) in single-game slates.  Anyone who followed his picks cashed in big.

Now, Kaylor has turned his attention to the Week 7 49ers vs. Vikings matchup on Monday Night Football and just locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.

Top NFL DFS picks for Vikings vs. 49ers on MNF

One of Kaylor's top NFL DFS picks for Monday Night Football is 49ers wide receiver Brandon Aiyuk. The former Arizona State standout has developed into the player the 49ers expected him to be when they took him in the first round of the 2020 NFL Draft. He put together his first career 1,000-yard receiving season in 2022 and is on pace to eclipse those numbers in 2023. For the season, Aiyuk has 25 receptions for 454 yards and two touchdowns. He averages just over six targets per game, but Kaylor expects that number to increase on Monday Night Football.

"The 49ers are banged up and coming off their worst offensive performance of the season. Deebo Samuel is out and Christian McCaffrey will likely be limited if he plays at all. I expect Kyle Shanahan to shift a big chunk of Samuel's and McCaffrey's touches and targets to Aiyuk, which should result in a massive performance from the former Arizona State Standout on Monday night," Kaylor told SportsLine.

Part of Kaylor's MNF DFS strategy also includes rostering Minnesota tight end T.J. Hockenson. The former first-round pick out of Iowa has developed into one of the top tight ends in the NFL and has a solid rapport with quarterback Kirk Cousins. With Justin Jefferson sidelined, Hockenson's role in the Minnesota offense has increased and Kaylor expects that to show on MNF.

"The 49ers' defense is elite on every level, but I still have T.J. Hockenson projected to be one of the top DFS options on Monday night. With Justin Jefferson still sidelined, Hockenson is Kirk Cousins' top target in the Minnesota offense. I expect the 49ers to get up early, forcing Minnesota to throw the ball more often than planned. San Francisco is a tough matchup for anyone, but I expect the volume to be there for Hockenson to have a productive fantasy night on MNF," Kaylor said. You can see the rest of Kaylor's NFL DFS picks here.

How to build NFL DFS lineups for 49ers vs. Vikings on MNF

Kaylor is also targeting another undervalued player who could explode for huge numbers for Monday Night Football. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of Kaylor's MNF DFS picks, at SportsLine. 

So who is Jimmie Kaylor including in his optimal NFL DFS lineups for Monday Night Football, and which under-the-radar NFL DFS picks offer sky-high value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a DFS expert who already won a single-game millionaire maker tournament, and find out.