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It's a matchup of ACC teams going in opposite directions when the No. 9 Duke Blue Devils host the Florida State Seminoles on Saturday at Cameron Indoor Stadium. Duke (22-4, 12-3) has won eight of its past nine games, while FSU (13-11, 6-8) has lost six of seven. The Seminoles beat the Blue Devils 79-78 in overtime on Jan. 18, but they have since suffered injuries to several top players. Both teams hung on for close victories in their most recent games on Tuesday night. FSU snapped a six-game losing skid with an 81-80 victory against Clemson, while Duke edged Wake Forest 76-74.

Tipoff in Durham, N.C. is set for 6 p.m. ET. Caesars Sportsbook lists the Blue Devils as 15-point favorites in its latest Florida State vs. Duke college basketball odds, and the over-under for total points scored is 142.5. Before locking in any Duke vs. Florida State picks, be sure to check out the college basketball predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,000 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Duke vs. FSU, and just locked in its picks and CBB predictions. You can visit SportsLine now to see the picks. Here are the college basketball odds and betting lines for FSU vs. Duke:

  • Duke vs. FSU spread: Blue Devils -15
  • Duke vs. FSU over-under: 142.5 points
  • Duke vs. FSU money line: Seminoles +900, Blue Devils -1700
  • FSU: The underdog is 5-1 ATS in the last six meetings.
  • DUKE: The home team is 7-3 ATS in the last 10 meetings.

Why Duke can cover 

Duke leads the ACC in scoring at 79.8 per game, while FSU scores less than 72 points. The Seminoles are 11th in scoring defense, giving up 70.6 per game, while the Blue Devils are third at 65.1. Duke is the second-best shooting team in the conference (48.2 percent), and with FSU relying on big men, there should be plenty of open looks. Tanor Ngom is a rim protector, but Mark Williams, also a 7-footer, is more athletic. He averages 10.6 points and 6.8 rebounds.

Duke hits 36.6 percent of its 3-point tries (49th in the nation), led by Wendell Moore Jr. at 40.4 percent. FSU opponents shoot better than 44 percent from the field, which ranks 238th in Division I and last in the ACC. The Blue Devils lead the conference in blocked shots at 5.5, with Williams swatting away three per game. Paolo Banchero leads the Blue Devils in scoring (16.9 points per game) and rebounds (8.5), and he had 20 points and 12 boards in the last meeting. 

Why Florida State can cover

Florida State will be desperate to build on Tuesday's victory after its dismal run. Injuries have been the main reason for that, but top scorer Caleb Mills (12.7 points per game) could be back for this one. He is a game-time decision because of an ankle injury. The Seminoles have been banking on its 7-footers as they scramble to compete despite the losses. They could present a matchup problem for the smaller Blue Devils, who tend to rely on their shooters to win.

Ngom (7-foot-2) had three blocked shots against Clemson, and 7-foot-1 John Butler has some range and can hit from outside (40.3 percent on threes). Matthew Cleveland (10.6 points) is second behind Mills in scoring, and RayQuan Evans averages 8.4. Cam'Ron Fletcher had 17 off the bench Tuesday. The Noles average 9.1 steals per game, with Mills averaging 1.6 and Evans 1.5, and they are third in the ACC in both turnover margin (plus-2.6) and blocked shots (4.4).    

How to make Florida State vs. Duke picks

SportsLine's model is leaning over on the total, projecting 146 combined points. It also says one side of the spread hits well over 50 percent of the time. You can only get the model's pick at SportsLine. 

So who wins Duke vs. FSU? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up almost $2,000 on its college basketball picks the last five-plus years, and find out.