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The Nebraska Cornhuskers (7-20) host the No. 25 Iowa Hawkeyes (19-8) in a key Big Ten matchup at 9 p.m. ET on Friday, Feb. 25 at Pinnacle Bank Arena in Lincoln. Nebraska lost to Northwestern 77-65 on Tuesday, extending its losing streak to three games. Iowa, on the other hand, is coming off two huge conference wins over Ohio State on Feb. 19 and Michigan State on Feb. 22. Iowa leads the all-time series 23-13.

Iowa is favored by 11 points in the latest Nebraska vs. Iowa odds from Caesars Sportsbook, and the over-under is set at 161.5. Before making any Iowa vs. Nebraska picks, you need to see the college basketball predictions and betting advice from the red-hot computer simulation model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,000 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Nebraska vs. Iowa, and just locked in its picks and CBB predictions. You can head to SportsLine now to see the model's picks. Here are several college basketball odds and betting lines for Nebraska vs. Iowa:

  • Nebraska vs. Iowa spread: Nebraska +11
  • Nebraska vs. Iowa over-under: 162 points
  • Nebraska vs. Iowa moneyline: Iowa -900, Nebraska +600

What you need to know about Nebraska

The contest between Nebraska and the Northwestern Wildcats on Tuesday was not a total blowout, but with Nebraska falling 77-65 on the road, it was darn close to turning into one. The top scorers for Nebraska were freshman guard Bryce McGowens (15 points), guard Alonzo Verge Jr. (15 points), and guard Kobe Webster (13 points).

With a 1-15 record in Big Ten play, Nebraska has obviously had a season to forget. Despite his team's struggles, it was announced that Fred Hoiberg will return as the Huskers' coach next season. One bright spot for Nebraska has been the play of McGowens, who is averaging 16.7 points and 5.4 rebounds per game. The Huskers are 13-14 against the spread in 2021-22. 

What you need to know about Iowa

Meanwhile, Iowa made easy work of the Michigan State Spartans on Tuesday and carried off an 86-60 win. The Hawkeyes' forward Keegan Murray did his thing and had 28 points along with five boards.

On paper, this game tilts heavily in Iowa's favor. The Huskers are giving up an average of 79.3 points per game (352nd most in the country), while the Hawkeyes are scoring 83.6 points per game (fourth most in college basketball). Murray is one of the premier players in the Big Ten, with the sophomore forward averaging 23.5 points and 8.1 rebounds per game. Iowa is 16-11 against the spread in 2021-22.

How to make Nebraska vs. Iowa picks

The model has simulated Nebraska vs. Iowa 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in 70 percent of simulations. You can only see the model's Iowa vs. Nebraska pick at SportsLine.

So who wins Iowa vs. Nebraska? And which side of the spread hits 70 percent of the time? Visit SportsLine now to see which side of the Nebraska vs. Iowa spread to jump on, all from the advanced model that is up almost $2,000 on its top-rated college basketball spread picks over the last five-plus years, and find out.