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No. 10 Kentucky (7-1) goes on the road to play Notre Dame (5-4) in Saturday afternoon college basketball action. The Wildcats will look to extend their win streak to eight games. Kentucky beat Southern University 76-64 on Dec. 7 in its last game. Notre Dame has been in a slump lately, dropping three games in a row. The Fighting Irish lost to Boston College 73-57 in their last outing.

Tipoff is set for 5:15 p.m. ET in South Bend, Ind. Caesars Sportsbook lists the Wildcats as 4.5-point road favorites in the latest Kentucky vs. Notre Dame odds. The over-under for total points is set at 142.5, down 3.5 points from the opening line. Before making any Notre Dame vs. Kentucky picks, be sure to check out the college basketball predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Kentucky vs. Notre Dame and just locked in its picks and CBB predictions. You can visit SportsLine now to see the model's picks. Here are the college basketball odds and betting lines for Notre Dame vs. Kentucky:

  • Kentucky vs. Notre Dame spread: Kentucky -4.5
  • Kentucky vs. Notre Dame over-under: 142.5 points
  • Kentucky vs. Notre Dame money line: Kentucky -200, Notre Dame +170
  • UK: Under is 5-1 in Wildcats last six games as a favorite
  • ND: Over is 5-1 in Fighting Irish last six games following a straight-up loss

Why Kentucky can cover 

Kentucky junior forward Oscar Tshiebwe is a double-double machine. He has recorded a double-double in seven games this year while averaging 15.3 points per game. Tshiebwe is first in the SEC in rebounds (15.4) and field-goal percentage (65.8). In the win against Southern University, he finished with 23 points, 11 rebounds, and four blocks.

Freshman guard TyTy Washington Jr. is second on the team with 14.8 points and 4.9 rebounds. The Arizona native has scored in double figures in seven straight games. The best game of his young career came against Ohio. Washington Jr. had 20 points, 12 rebounds and five assists. 

Why Notre Dame can cover

Junior guard Dane Goodwin is averaging a team-best 14.3 points, 5.4 rebounds and is shooting 42 percent from 3-point range. Goodwin has scored in double figures in every game he's played in this season. The Ohio native has also knocked down at least three 3-pointers in three games. Against Cal State Northridge, Goodwin finished with 18 points and shot 6 of 8 from 3-point range.

Freshman guard Blake Wesley logs 12.9 points per game. Wesley has scored over 20 points in two games so far. In the loss to Illinois, he recorded a season-high 24 points with three boards. Wesley also shot a season-best 9 of 12 from the floor. Junior forward Nate Laszewski is averaging 8.6 points and 9.1 rebounds per game.

How to make Notre Dame vs. Kentucky picks

SportsLine's model is leaning under on the total, projecting 143 combined points. It has also generated an against-the-spread pick that cashes in over 50 percent of simulations. You can only get the model's pick at SportsLine. 

So who wins Kentucky vs. Notre Dame? And which side of the spread hits in over 50 percent of simulations? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up over $2,200 on its college basketball picks the last five years, and find out.