Nolan Arenado
USATSI

The season series between the Chicago White Sox and Minnesota Twins has been one-sided, to say the least. Chicago has won 10 of the 12 contests between the American League Central rivals, including all six at Guaranteed Rate Field. The division-leading White Sox attempt to remain perfect at home against the Twins when the clubs begin a four-game set with Game 1 of a doubleheader on Monday. Chicago has won seven of its last eight overall contests, while Minnesota has lost three straight after entering the All-Star break with a four-game winning streak.

First pitch for this seven-inning game is scheduled for 5:10 p.m. ET. Minnesota sends rookie Griffin Jax (101, 8.66 ERA) to the mound against fellow right-hander Lance Lynn (9-3, 1.99). Chicago is the -219 favorite (risk $219 to win $100) on the money line at William Hill Sportsbook, while the over-under for runs scored is seven in the latest Twins vs. White Sox odds. Before making any White Sox vs. Twins picks, check out the latest MLB predictions from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line MLB picks. In the first half of the 2021 season, it went 120-96 on top-rated MLB money-line picks, returning almost $400. Anyone following it has seen huge returns.

Now, the model has locked in its Twins vs. White Sox picks and predictions. You can visit SportsLine now to see the picks. Here are the MLB odds and trends for White Sox vs. Twins:

  • Twins vs. White Sox money line: Minnesota +199, Chicago -219
  • Twins vs. White Sox run line: Chicago -1.5
  • Twins vs. White Sox over-under: 7 runs
  • MIN: The Twins have lost eight of their last nine road games
  • CWS: The White Sox have scored four or more runs in seven of their last eight contests

Why you should back the White Sox

Tim Anderson has been dialed in at the plate as he enters Monday with a career high-tying 15-game hitting streak. The 28-year-old All-Star also has crossed the plate in 11 straight contests, setting a franchise record for most consecutive games with both a hit and a run scored. Anderson, who has homered in back-to-back contests, has hit safely in each of his last five meetings with the Twins.

The White Sox also have received solid production of late from Adam Engel, who has gone 7-for-20 with three multi-hit performances in his last five games. The 29-year-old outfielder has belted a pair of home runs, collected eight RBIs and scored five times in that span. Lynn, who has yielded two runs over 15 innings in his last three turns, looks to give Chicago its third straight strong effort from its starting pitcher after Lucas Giolito and Carlos Rodon combined to allow one run and four hits with 18 strikeouts over 16 frames against Houston over the weekend.

Why you should back the Twins

Minnesota's offense has stumbled out of the gate in the second half, producing a total of four runs during the team's three-game series at Detroit this past weekend. Although the Twins haven't won at Guaranteed Rate Field this season, they've managed to score five or more runs in three of the six contests. Minnesota managed only six hits in Sunday's 7-0 loss to the Tigers, with Luis Arraez and Trevor Larnach recording two apiece.

Arraez has been swinging a hot bat of late, hitting safely in nine of his last 10 contests. The 24-year-old second baseman has registered five multi-hit performances in that span and went 5-for-12 during a three-game set against Chicago from July 5-7. Larnach is 3-for-7 with a homer against Lynn while Miguel Sano has notched three hits -- two solo blasts -- in five career at-bats versus the veteran hurler.

How to make Twins vs. White Sox picks

SportsLine's model is leaning over on the run total, as the simulations project the teams will combine for 7.9 runs, and it also says one side of the money line has the value. You can only get the model's MLB picks at SportsLine. 

So who wins Twins vs. White Sox? And which side of the money line has all the value? Visit SportsLine now to see which side of the White Sox vs. Twins money line to jump on Monday, all from the advanced model that has returned nearly $400 on MLB picks in 2021, and find out.