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Wednesday will feature a 12-game NBA schedule. Among the notable NBA odds include Bulls vs. Pistons (-9.5), Nuggets vs. Celtics (-9.5), Magic vs. Nets (+2.5), Clippers vs. Knicks (-4.5), Suns vs. Grizzlies (+4.5), Lakers vs. Spurs (-7.5) and Bucks vs. Warriors (-5.5). Boston looks to extend its winning streak to five games, while the Knicks look to snap a four-game losing skid.

What are the NBA best bets for Wednesday, and which combination of picks should you target in a Wednesday NBA parlay? Before locking in any NBA picks, you'll want to see the NBA predictions and betting advice from SportsLine's proven computer model.

New users can target the DraftKings promo code, which offers $300 in bonus bets if your bet wins:

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model enters Week 12 of the 2025-26 NBA season on a sizzling 33-15 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.

Now, the model has scoured the latest NBA odds and locked in three confident NBA best bets. If you successfully parlay its picks, you'd be looking at a payout of over +600. You can only see the model's NBA picks at SportsLine.

New users can also check out the latest FanDuel promo code and get $300 in bonus bets instantly at FanDuel if your $5 bet wins:

Top NBA picks for Wednesday, Jan. 7

After simulating every game 10,000 times, the model is backing the Celtics (-9.5) to cover the spread against the Nuggets in Boston at 7 p.m. ET. The Nuggets have lost seven of their last 10 meetings with the Celtics, including each of the last two games. 

The model is projecting five Celtics players to score 11.7 points or more, led by Jaylen Brown's 30.1 points. The Nuggets meanwhile, have lost four of six and are still without Nikola Jokic (knee) and several other key contributors, so the model is backing Boston despite laying 9.5 points on Wednesday. See which other NBA parlay picks to make here.

How to make NBA predictions for Wednesday, Jan. 7

The model also has locked in two more picks, including another bet that hits nearly 70% of the time. You can only see the model's NBA parlay at SportsLine.

What are the model's top NBA parlay picks for Wednesday, and which best bets should you target for a chance at a payout of over +600? Visit SportsLine now to see NBA best bets from a model that's returned more than $10,000 on top-rated picks, and find out.