Bears vs. 49ers odds, line, spread: 2021 NFL picks, Week 8 predictions from proven computer model

SportsLine's model just revealed its NFL picks for Niners vs. Bears

By Scout Staff

Oct 31, 2021 at 11:14 am ET • 2 min read

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The Chicago Bears host the San Francisco 49ers in an NFC battle on Sunday. The Bears are coming off a lopsided 38-3 defeat to the Tampa Bay Buccaneers. San Francisco, meanwhile, enters Sunday's showdown having lost each of its last four games.

Kickoff from Soldier Field is at 1 p.m. ET. San Francisco is favored by four points in the latest Bears vs. 49ers odds from Caesars Sportsbook, and the over-under is set at 40. Before entering any 49ers vs. Bears picks, you'll want to see the NFL predictions from the model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up almost $7,700 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 8 of the 2021 NFL schedule on an incredible 126-85 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Bears vs. 49ers. You can head to SportsLine to see its picks. Here are several NFL betting lines for Niners vs. Bears:

Bears vs. 49ers spread: 49ers -4
Bears vs. 49ers over-under: 40 points

What you need to know about the Bears

Chicago's 35-point loss to Tampa Bay was the Bears' worst defeat in seven years. Justin Fields committed five turnovers, throwing three interceptions while being sacked five times. He has been sacked an NFL-high 22 times this season. The Bears rank last in the NFL in passing at 124.4 yards per game and Fields has thrown two TD passes with six interceptions.

Chicago is the only team in the league to average more rushing yards per game than passing yards, as the Bears are at 131 per game. Khalil Herbert rushed for 100 yards and had five receptions for 33 yards last week. Khalil Mack (foot) is out for Sunday's game and Akiem Hicks (groin) is questionable.

What you need to know about the 49ers

The 49ers have been dealing with a number of injuries this season, but running back Elijah Mitchell finally seems healthy. San Francisco's rookie tailback is coming off a strong performance against the Colts, rushing 18 times for 107 yards and a touchdown. Mitchell is averaging 4.7 yards per carry and he's expected to be heavily involved against the Bears on Sunday.

That's because Mitchell is the only rookie in the league with two 100-yard rushing games this season. Plus, Chicago's defense is giving up 122.1 rushing yards per game. In addition, the 49ers have covered the spread in 13 of their last 19 meetings against the Bears.