Two of the NFL's most explosive offenses will square off when Patrick Mahomes and the Kansas City Chiefs take on Dak Prescott and the Dallas Cowboys on Sunday. The Cowboys (7-2) lead the league in scoring at 31.6 points per game, while the Chiefs (6-4) are third at 31.0. Kansas City is a 2.5-point favorite in the latest NFL odds from Caesars Sportsbook, but which team should you back with your NFL bets and NFL parlays?

The game is one of 15 on the Week 11 NFL schedule. Other key NFL matchups include Washington coach Ron Rivera facing his former team (Carolina) and quarterback (Cam Newton) and the Chargers hosting the Steelers on Sunday Night Football. Before making any Week 11 NFL picks or predictions, you need to check out the NFL best bets from the proven computer model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up almost $7,500 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 11 of the 2021 season on an incredible 128-89 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 11. If you successfully parlay its picks, you'd be looking at a massive payout of 25-1. You can only see the model's Week 11 NFL picks at SportsLine. 

Top Week 11 NFL picks

After simulating every game 10,000 times, the model is high on the Panthers to cover as 3.5-point favorites at home against the Washington Football Team. Carolina (5-5) has won two of its last three games and is coming off its best performance of the season, a 34-10 dismantling of the Cardinals, who had entered the game with the best record in the NFL. Also last week, Washington (3-6) ended a four-game losing streak with a 29-19 upset of Tom Brady and Tampa Bay.

The Panthers face a Washington team that has struggled on the road this season. The Football Team is 1-3 away from home this year, with its only victory coming at Atlanta. Washington has scored just 75 points in its four road games and been outscored by an average of 9.8 points per game. In its last two road games, Washington has scored exactly 10 points.

How to make Week 11 NFL parlays

The model also jumped on four other matchups where it says the line is way off, including a divisional battle and a game between two teams fighting for their playoff lives. You can only see the model's NFL Week 11 best bets and parlay at SportsLine. 

What are the model's top Week 11 NFL picks? And which other matchups should you target for an epic 25-1 payout? Visit SportsLine now to see the Week 11 NFL best bets from a model on a 128-89 run on its top-rated picks, and find out.