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Arsenal will try to maintain their place at the top of the English Premier League table on Wednesday when they host Aston Villa at Emirates Stadium. The Gunners (4-0-0) finished a disappointing fifth in the EPL table last season, losing two of their final three games. But they bolstered what had been an ineffective attack during the summer and are now the only EPL team to win every game this season. They cruised past Crystal Palace, Leicester and Bournemouth in their first three games but found themselves in a fight with Fulham last Saturday. They pulled off a 2-1 victory to maintain their run and now face the struggling Villans in London. Villa (1-3-1) is playing for Steven Gerrard's job, as the manager has won just 16 of 31 matches since taking over, despite a solid talent base on paper. 

Kickoff is set for 2:30 p.m. ET. Caesars Sportsbook lists Arsenal as the -180 favorite (risk $180 to win $100) on the 90-minute money line in its latest Arsenal vs. Aston Villa odds. The Villans are a +500 underdog, a regulation draw is priced at +310 and the over/under for total goals scored is 2.5. Before you make any Aston Villa vs. Arsenal picks, you have to see what proven SportsLine soccer insider Jon Eimer has to say. 

Eimer is a high-volume bettor who has vast knowledge of leagues and players across the globe. Since joining SportsLine, Eimer has covered the English Premier League, Serie A, the FA Cup and much more. He is 28-17-1 on his Premier League picks for SportsLine in 2022, for a profit of more than $1,000 for $100 bettors, and he is 66-50-1 on his last 117 soccer picks overall.

Now, Eimer has broken down the Arsenal vs. Aston Villa matchup from all sides and just locked in his picks and EPL predictions. You can head to SportsLine now to see his picks. Here are the betting lines and trends for Aston Villa vs. Arsenal:

  • Arsenal vs. Aston Villa spread: Arsenal -1.5 (+150)
  • Arsenal vs. Aston Villa over-under: 2.5 goals 
  • Arsenal vs. Aston Villa money line: Arsenal -180, Aston Villa +500, Draw +310 
  • ARS:  The Gunners have a 23-12 goal advantage in their past 10 matches (8-0-2) 
  • AV: The Villans have been outscored 15-13 in their past 10 matches (3-5-2) 
  • Arsenal vs. Aston Villa picks: See picks here.

Why you should back Arsenal

The Gunners are playing at home and are much more rested, as this will be Villa's fourth match in 11 days. They played Sunday after a Wednesday League Cup match. They could be weary, which will be a problem against an Arsenal attack energized by the arrival of Gabriel Jesus from Manchester City. The Brazilian had eight goals and eight assists while starting 21 of his 28 appearances for City last season. He already has two goals and three assists in the first four matches and has sparked a fire under Martin Odegaard, Bukayo Saka and Gabriel Martinelli.

Odegaard scored his third goal of the season Saturday, and Martinelli has scored twice, while Saka is a playmaker all over the field. The Gunners are averaging 2.5 goals per 90 minutes after posting a 1.58 mark last season. They had a plus-18 home goal differential last season and earned 41 of their 69 points at the Emirates. The visitors lost 11 of 19 games away from Villa Park, the fourth-most road losses in the league, and scored 23 goals on the road. Arsenal have won eight of the past 11 meetings and are 6-1-1 in their past eight Wednesday fixtures. 

Why you should back Aston Villa

Before losing both meetings last season, Aston Villa had won three straight matches with Arsenal. The Villans have struggled in league play, but they did get a 4-1 victory against Bolton in an EFL Cup match last Wednesday, and they clearly have dangerous attackers. Ollie Watkins, Leon Bailey and Jacob Ramsey are all talented playmakers, and Bailey was one of the goal-scorers Wednesday. The Jamaican has one assist in league play, while Watkins has one goal while setting up two. Watkins has scored 25 goals over the past two seasons for Villa, and Ramsey scored six in 2021-22. 

Philippe Coutinho should support Watkins and Bailey, and he had five goals and three assists last year. Danny Ings, who started the past two games but could rest on the quick turnaround, had seven goals while setting up six last season, The attack also gets a jolt from the back line, with Matty Cash, Tyrone Mings and Lucas Digne often joining the fray. Cash scored four goals and set up three last year, and John McGinn, who had four goals and three assists, is an important piece in the middle. The captain is third in the EPL in progressive passes (32), while Digne is third in crosses (23).

How to make Arsenal vs. Aston Villa picks

Eimer has analyzed Arsenal vs. Aston Villa from every angle. He is taking the Over on the goal total and has two other confident best bets, along with his full breakdown of the match. He's only sharing his Premier League picks and analysis here.

So who wins Aston Villa vs. Arsenal? And where does all the betting value lie? Visit SportsLine now to see the best bets for Arsenal vs. Aston Villa, all from the soccer expert who has his finger on the pulse of the game all over the world, and find out.