NCAA Basketball: Vanderbilt at Louisiana State
Stephen Lew / USA TODAY Sports

The No. 11 Auburn Tigers and the No. 16 LSU Tigers are set to square off in an SEC showdown at 7 p.m. ET on Wednesday at Auburn Arena. Auburn is 11-1 overall and 6-0 at home, while LSU is 12-0 overall and 0-0 on the road. LSU picked up a 104-80 victory at home when these teams met last season. 

Auburn is favored by four points in the latest Auburn vs. LSU odds from Caesars Sportsbook, while the over-under is set at 142. Before entering any LSU vs. Auburn picks, you'll want to see the college basketball predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Auburn vs. LSU. You can head to SportsLine to see its picks. Here are several college basketball odds for Auburn vs. LSU:

  • Auburn vs. LSU spread: Auburn -4
  • Auburn vs. LSU over-under: 142 points

What you need to know about Auburn

The stars were brightly shining for Auburn in a 71-58 win over the Murray State Racers last week. Among those leading the charge for Auburn was forward Walker Kessler, who had 13 points in addition to seven blocks and seven rebounds. Wendell Green Jr. added 13 points and 10 rebounds in just 19 minutes off the bench. 

Jabari Smith also had a double-double for Auburn, scoring 12 points and grabbing 10 rebounds. The Tigers have struggled with rebounding this season, but they recorded a 48-33 advantage against Murray State. Auburn has covered the spread in six of its last eight games. 

What you need to know about LSU

LSU was too much for Lipscomb to handle in its last game, picking up a comfortable 95-60 win. Forward Darius Days was the offensive standout for the Tigers, finishing with 21 points and six rebounds. Xavier Pinson added 17 points and the Tigers shot 12-of-22 from beyond the arc. 

LSU comes into Wednesday's contest boasting the sixth most takeaways per game (19.5) in college basketball. Sophomore forward Tari Eason is scoring a team-high 16.3 points per game, despite coming off the bench in all 11 of his outings. LSU has covered the spread in 16 of its last 19 games dating back to last season. 

How to make Auburn vs. LSU picks

The model has simulated Auburn vs. LSU 10,000 times and the results are in. We can tell you that the model is leaning over, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You can only see the pick at SportsLine.

So who wins LSU vs. Auburn? And which side of the spread covers almost 70 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its college basketball picks.