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The No. 2 Gonzaga Bulldogs and the BYU Cougars will face off in a West Coast clash at 10 p.m. ET on Saturday at the Marriott Center. BYU is 17-7 overall and 10-1 at home, while the Bulldogs are 18-2 overall and 2-0 on the road. Gonzaga has won 10 of the last 11 meetings between these teams, with BYU's win coming in February of 2020. 

The Bulldogs are favored by 12.5 points in the latest BYU vs. Gonzaga odds from Caesars Sportsbook, while the over-under is set at 157.5. Before entering any Gonzaga vs. BYU picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Brigham Young vs. Gonzaga. You can head to SportsLine to see its picks. Here are several college basketball odds for Gonzaga vs. Brigham Young:

  • Gonzaga vs. BYU spread: Gonzaga -12.5
  • Gonzaga vs. BYU over-under: 158 points

What you need to know about BYU

BYU has quickly found itself on the NCAA Tournament bubble following a three-game losing streak. The Cougars were favored in all three setbacks, including a 76-73 loss at Pacific as 13-point favorites. They have an opportunity to get off the bubble with an upset win at home on Saturday night. 

Senior guard Alex Barcello leads BYU with 17.3 points and 3.0 assists per game. Senior guard Te'Jon Lucas is the only other player in double figures, averaging 10.4 points The Cougars generally find a way to win at home, coming out victorious in 12 of their last 13 games at the Marriott Center. 

What you need to know about Gonzaga

Outside of losses to Alabama and Duke in non-conference play, Gonzaga has been nearly untouchable this season. The Bulldogs have certainly not been challenged within the WCC, winning all seven of their conference games by double digits. They are coming off a 92-62 win over San Diego on Thursday night. 

Star freshman Chet Holmgren scored a career-high 23 points and completed his double-double with 12 rebounds in the win over San Diego. Holmgren is averaging 19.5 points, 10.3 rebounds and 3.0 blocks over his last four games. Gonzaga is currently riding a nine-game road winning streak. 

How to make Gonzaga vs. BYU picks

The model is leaning under on the total, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Gonzaga vs. BYU? And which side covers almost 60 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its college basketball picks.