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A Big East battle is on tap between the Georgetown Hoyas and the Seton Hall Pirates at 7 p.m. ET Wednesday at the Prudential Center. Georgetown is 6-22 on the season and 0-17 in conference play while Seton Hall is 18-9 and 9-8 in the Big East. Seton Hall has actually won 11 of the last 15 meetings in this head-to-head matchup but the Hoyas have won two of three and are 2-0-1 against the spread during that span.

This season, both teams have struggled against the spread with Seton Hall going 12-14 against the number while Georgetown is 12-15. The Pirates are favored by 13 points in the latest Seton Hall vs. Georgetown odds and the over-under is set at 145. Before you make any Georgetown vs. Seton Hall picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $1,700 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Seton Hall vs. Georgetown. You can head to SportsLine to see its picks. Here are several college basketball odds for Georgetown vs. Seton Hall:

  • Seton Hall vs. Georgetown spread: Seton Hall -13
  • Seton Hall vs. Georgetown over-under: 145 points

What you need to know about Seton Hall

Seton Hall is coming off an impressive 82-66 win over Xavier on Saturday. The Pirates shot 52.7 percent from the floor as a team and Jared Rhoden put in a monster effort offensively. Rhoden shot 8-for-14 from the floor and went 12-for-13 from the free-throw line to score 30 points in the victory.

The fourth-year wing is now averaging 16.1 points per game and has racked up 1,206 points in his career at Seton Hall. Tray Jackson also had 17 points in the victory and he was the team's leading scorer in a Feb. 1 win over the Hoyas, pouring in 21 points in a 70-63 win.

What you need to know about Georgetown

The Hoyas are coming off a hard-fought 86-77 loss to Connecticut on Sunday. Dante Harris led all scorers with 23 points in the loss and freshman Aminu Mohammed overcame a 2-for-10 shooting night to score 16 points by making 15 trips to the free-throw line and knocking down 12 of those freebies.

Mohammed will have to continue getting downhill to attack the Seton Hall defense if the Hoyas are going to end their Big East losing streak. The former five-star recruit is averaging 14.1 points and 8.0 rebounds per game this season and he just about matched those averages with 14 points and eight rebounds in the loss to the Pirates on Feb. 1.

How to make Georgetown vs. Seton Hall picks

The model has simulated Seton Hall vs. Georgetown 10,000 times and the results are in. We can tell you that the model is leaning under and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Seton Hall vs. Georgetown? And which side of the spread hits well over 50 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its college basketball picks.