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The No. 16 USC Trojans (23-4) hit the road to take on the Oregon State Beavers (3-22) n a Pac-12 clash at 11 p.m. ET on Thursday, Feb. 24 at Gill Coliseum in Corvallis. USC won a 62-60 nail biter against Washington State on Feb. 20, extending its winning streak to four games. The Beavers have lost 12 straight contests and are in the midst of one of the worst seasons in program history.

USC is favored by 10.5 points in the latest Oregon State vs. USC odds from Caesars Sportsbook, and the over-under is set at 139.5. Before making any USC vs. Oregon State picks, you need to see the college basketball predictions and betting advice from the red-hot computer simulation model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,000 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Oregon State vs. USC, and just locked in its picks and CBB predictions. You can head to SportsLine now to see the model's picks. Here are several college basketball odds and betting lines for Oregon State vs. USC:

  • Oregon State vs. USC spread: Oregon State +10.5
  • Oregon State vs. USC over-under: 140 points

What you need to know about Oregon State

The Beavers suffered a grim 73-53 defeat to the Arizona State Sun Devils on Saturday. Guard Jarod Lucas had a rough night: he finished with only four points on 2-for-11 shooting in his 30 minutes on the court.

Oregon State has struggled mightily this season. If their overall record of 3-22 weren't enough proof of the Beavers' struggles, the fact that they've been blown out in the majority of their losses should drive the point home. Oregon State has allowed their opponents to shoot 46.90% from the floor on average, which is the ninth highest shooting percentage allowed in college basketball. The Beavers are 6-18-1 against the spread in 2021-22. 

What you need to know about USC

Meanwhile, the Trojans skirted by the Washington State Cougars 62-60 on Sunday thanks to a clutch half-court bomb from guard Boogie Ellis with 0:03 left to play. Among those leading the charge for USC was Ellis, who had 21 points.

USC's defense has been outstanding in 2021-22, holding their opponents to a field goal percentage of 37.50%, which is the fifth best mark in college basketball. Forward Isaiah Mobley is one of the best players in the Pac-12, with the junior averaging 14.4 points, 8.3 rebounds, and 3.4 assists per game. USC is 13-14 against the spread in 2021-22.

How to make USC vs. Oregon State picks

The model has simulated Oregon State vs. USC 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the model's pick at SportsLine.

So who wins Oregon State vs. USC? And which side of the spread hits over 60 percent of the time? Visit SportsLine now to see which side of the USC vs. Oregon State spread to jump on, all from the advanced model that is up almost $2,000 on its top-rated college basketball spread picks over the last five-plus years, and find out.