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The No. 10 Villanova Wildcats and the Georgetown Hoyas are set to square off in a Big East matchup at 5 p.m. ET on Saturday at Finneran Pavilion. The Wildcats are 20-6 overall and 10-1 at home, while Georgetown is 6-19 overall and 0-8 on the road. Villanova picked up an 85-74 road win in the first meeting between these teams this season. 

The Wildcats are favored by 20 points in the latest Villanova vs. Georgetown odds from Caesars Sportsbook, while the over-under is set at 144.5. Before entering any Georgetown vs. Villanova picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,000 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Villanova vs. Georgetown. You can head to SportsLine to see its picks. Here are several college basketball odds for Georgetown vs. Villanova:

  • Villanova vs. Georgetown spread: Villanova -20
  • Villanova vs. Georgetown over-under: 144 points

What you need to know about Villanova

Villanova has bounced back from a loss at Marquette with a four-game winning streak. The Wildcats notched a huge road win on Tuesday over Big East-leading Providence in an 89-84 final. They are now one game back of the Friars in the conference standings, with a rematch looming on March 1. 

Senior guard Collin Gillespie leads Villanova with 16.8 points per game, while Justin Moore is scoring 15.3 points and Jermaine Samuels is adding 10.1 points. Eric Dixon is averaging 9.9 points and a team-high 6.8 rebounds per game. The Wildcats are on a nine-game home winning streak in their series with Georgetown. 

What you need to know about Georgetown

Georgetown has not won a game since beating Howard on Dec. 15. The Hoyas are winless in their conference games this season, including a 77-66 loss at Marquette on Wednesday. They did hold a four-point lead with less than 13 minutes remaining in their first meeting with Villanova this season, though. 

Aminu Mohammed scored 13 points and grabbed a career-best 17 rebounds in the loss to Marquette on Wednesday, notching his ninth double-double of the season. Mohammed leads Georgetown with 14.1 points and 8.1 rebounds per game, but he has three teammates scoring in double figures as well. The Hoyas have covered the spread in four of their last five games against Villanova. 

How to make Villanova vs. Georgetown picks

The model is leaning over on the total, and it also says one side of the spread has all the value. You can only see the pick at SportsLine.

So who wins Georgetown vs. Villanova? And which side has all the value? Visit SportsLine now to find out, all from the model that has crushed its college basketball picks.