SEC
- Top 25
- All FBS Games
- All FCS Games
- ACC
- American
- Big 12
- Big Sky
- Big South-OVC
- Big Ten
- Coastal Athletic Association
- Conference USA
- FBS Independents
- Independents (FCS)
- Ivy League
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- Missouri Valley
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- Northeast
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- SEC
- Southern
- Southland
- Southwestern Athletic
- Sun Belt
- United Athletic
Wednesday, December 22, 2021
| Away | Home | Result |
|---|---|---|
Thursday, December 23, 2021
| Away | Home | Result |
|---|---|---|
Notes
- All times are US/Eastern.
