Trammell was removed from Tuesday's game against the Orioles with an apparent leg injury, Kennedi Landry of MLB.com reports.
The 24-year-old hit into double play with the bases loaded to end the fourth inning, and he pulled up with an injury as he reached first base. Trammell dealt with a hamstring injury in the minors earlier this year, though it's unclear if he aggravated that injury or if he's dealing with a separate issue.