Sousa was designated for assignment by the Reds on Wednesday, Mark Sheldon of MLB.com reports.
Sousa was the 40-man roster casualty when the Reds selected the contract of fellow relief pitcher Kevin Herget. The left-hander appeared in 25 games with White Sox in 2022, struggling to a 8.41 ERA and 1.72 WHIP with 12 strikeouts over 20.1 innings.