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The Los Angeles Dodgers put their MLB-best nine-game winning streak on the line on Wednesday when they host the Milwaukee Brewers in the middle game of a three-game series at Dodger Stadium in Los Angeles. The Dodgers (72-46), who also have won 13 of their last 14, lead the National League West by nine games over the Giants. Meanwhile, the Brewers (65-55) lead the NL Central by 3.5 games over the Cubs and Reds. For Wednesday, Los Angeles is a -246 favorite in the latest MLB odds, while Milwaukee is a +200 underdog. The over/under for runs scored is 8.

The game is one of 15 on the MLB schedule for Wednesday. Elsewhere in the majors, the Braves will try to extend the Yankees' misery and complete a three-game sweep in Atlanta, and the Rangers look to sweep the Angels. Before making any MLB picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons. It entered Week 21 of the 2023 MLB season 61-47 on all top-rated MLB picks this season and has excelled on top-rated run-line picks, going 12-4 (+468). Anybody following has seen big returns.

For Wednesday, the model has locked in three confident MLB best bets for games that begin at 6:40 p.m. ET or later. If you successfully parlay the picks, you'd be looking at a payout of well over 9-1. You can see the model's MLB picks only at SportsLine

Top MLB picks today

The model, which ran 10,000 simulations on each of the 15 games on Wednesday, is taking Baltimore (+156) to knock off San Diego at Petco Park. The Orioles have the second best road record in all of baseball at 38-23. Meanwhile, the Padres, who were considered among the favorites in the NL to begin the season, are just 31-29 at home.

Dean Kremer is set to start for Baltimore on Wednesday, and the Orioles have had success with him on the mound. They have won 10 of the last 11 games Kremer has pitched, including each of the last seven. On Wednesday, Kremer faces a San Diego team that has struggled down the stretch, losing seven of its last nine games. See the model's top MLB picks here.

How to make Wednesday MLB parlays

The model also locked in two other best bets for Wednesday, including a play on an even bigger AL underdog, which would pay plus-money. You can see the model's MLB Wednesday best bets and parlay only at SportsLine.

What MLB picks should you target for a payout of well over 9-1, and which AL underdog should you be all over on Wednesday? Visit SportsLine now to see the MLB best bets from an advanced model that is 61-47 on all top-rated MLB picks this season, and find out.