2023 MLB playoff odds, ALDS, NLDS picks for Wednesday, Oct. 11 by proven model: This 3-way parlay returns 6-1

SportsLine's model has revealed its MLB picks, predictions, parlay and best bets for Wednesday, October 11

By CBS Sports Staff

Oct 11, 2023 at 3:15 pm ET • 2 min read

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The Arizona Diamondbacks can advance to the National League Championship Series for the first time since 2007 when they host the Los Angeles Dodgers in Game 3 of the NLDS at Chase Field in Phoenix. Arizona, which entered the 2023 MLB playoffs as the No. 6 seed, own a surprising 2-0 lead in the best-of-five series and, with a win on Wednesday, would advance to the NLCS to face either the Braves or Phillies. Meanwhile, the Dodgers are trying to force a Game 4 on Thursday in Phoenix. Los Angeles is a -131 favorite (risk $131 to win $100) in the latest MLB odds, while Arizona is a +111 underdog. The over/under for runs scored is 9.5, and first pitch is scheduled for 9:07 p.m. ET.

The game is one of three Division Series games on the MLB schedule for Wednesday. Elsewhere around the league, the Braves and Phillies collide in a crucial Game 3 with the series tied 1-1, and the Astros look to advance to their seventh straight ALCS with a win over the Twins. Before making any MLB Division Series picks or parlays, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons. It entered the second week of the 2023 MLB playoffs 92-74 on all top-rated MLB picks this season and has excelled on top-rated run-line picks, going 18-6 (+766). Anybody following has seen big returns.

For Wednesday's Division Series games, the model has locked in three MLB best bets. If you successfully parlay the picks, you'd be looking at a payout of more than 6-1. You can see the model's MLB picks only at SportsLine.

Top MLB picks for Wednesday

The model, which ran 10,000 simulations on each of the three games on Wednesday, is taking Houston to eliminate Minnesota. Twins starter Joe Ryan struggled down the stretch this season. After posting a 2.77 ERA over the first two months of the year, Ryan had a 6.09 ERA over the last three months of the season. Early in the year when he was pitching well, he faced the Astros twice and was touched up for nine earned runs over 10 innings (8.10 ERA), giving up seven hits and three home runs.

In addition, Houston has all of its high-leverage bullpen arms available for Wednesday's game. With Monday's day off and Tuesday's comfortable margin of victory, closer Ryan Pressly, Hector Neris and Ryne Stanek all should be fresh for Game 4. Though set-up man Bryan Abreu pitched on Tuesday, he threw just 12 pitches and also will be available. See the model's top MLB picks here.