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The Baltimore Orioles (48-58) and Toronto Blue Jays (63-44) will play on two on Tuesday with a doubleheader to make up for an April postponement. The first contest is a matinee between the AL East rivals, as Baltimore will look to continue its success from Monday it defeated Toronto, 11-4. The Orioles have now won two of three matchups between the teams this season, but these squads have alternated wins and losses over their last 11 meetings. Charlie Morton (6-8, 5.48 ERA) will take the ball for Baltimore, while Toronto is scheduled to start Easton Lucas (3-2, 5.82 ERA). Baltimore catcher Adley Rutschman, who returned on Monday from an oblique injury, is not in the starting lineup for Game 1 on Tuesday. 

First pitch for Game 1 is at 12:35 p.m. ET from Oriole Park at Camden Yards in Baltimore. Baltimore is a -123 favorite on the money line (risk $123 to win $100) in the latest Blue Jays vs. Orioles odds from FanDuel Sportsbook, while the over/under for total runs scored is 10. Before making any Orioles vs. Blue Jays picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 19 of the 2025 MLB season a profitable 27-22 on top-rated MLB money-line picks. It has excelled making home run prop picks this season, returning more than 40 units of profit. Anybody following at sportsbooks and on betting sites could have seen strong returns.

Now, the model has set its sights on Blue Jays vs. Orioles and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Blue Jays vs. Orioles, which you can get in on with a DraftKings promo code or a FanDuel promo code.

Blue Jays vs. Orioles money line

Toronto +103, Baltimore -123 at FanDuel

Blue Jays vs. Orioles over/under

10 runs

Blue Jays vs. Orioles run line 

Baltimore -1.5 (+156)

Blue Jays vs. Orioles picks

See picks at SportsLine

Blue Jays vs. Orioles streaming 

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Why the Blue Jays can win

There may be no hotter hitter in baseball than Bo Bichette, whose four-hit outing on Monday followed a five-hit game on Sunday. Bichette's current 10-game hitting streak is tied for the second-longest in the American League, and he just so happens to be tied with his teammate. Vladimir Guerrero Jr. also has knocks in 10 straight games, including hitting his 15th homer of the year in last night's outing.

The Blue Jays are 19-6 over their last 25 games and own the best record in the American League. They are the best hitting team in the majors, and it's not even close. Their .263 batting average tops MLB as does their .334 on-base percentage. See which team to back at SportsLine.

Why the Orioles can win

Baltimore's bats have come alive recently as they scored 11 runs in Monday's win over the Jays after scoring 18 runs in a Saturday shutout of Colorado. The O's clearly enjoy the friendly confines of Camden Yards as the team's OPS is significantly higher at home (.776) than on the road (.657). That's a bad sign for a Jays offense which has hit 26 fewer home runs on the road than at home, despite playing just one fewer away game.

At the beginning of the year, 41-year-old Morton looked every bit of his age, with a 9.38 ERA through his first nine games. However, he's settled down and has a 3.53 ERA over his last 13 games. See which team to back at SportsLine. 

How to make Blue Jays vs. Orioles picks

SportsLine's model is leaning Under on the total, and it says one side of the money line has all the value. You can head to SportsLine to see the model's MLB picks. 

So who wins Blue Jays vs. Orioles, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.