seiya-suzuki-getty-images-cubs.jpg
USATSI

The St. Louis Cardinals (26-21) host the San Diego Padres (30-17) as these teams kick off their three-game series on Monday afternoon. The Padres have gone 7-3 in their last 10 games. On the flip side, St. Louis is 6-4 over its past 10 outings. Packy Naughton (0-1, 2.89 ERA) gets the start for St. Louis. Nick Martinez (2-2, 3.86 ERA) is on the hill for San Diego.

The first pitch is set for 2:15 p.m. ET. Caesars Sportsbook lists St. Louis as the slight -120 money-line favorite (risk $120 to win $100) in the latest Padres vs. Cardinals odds. The over-under for total runs is set at nine. Before locking in any Cardinals vs. Padres picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a strong start to the 2022 season. It's on a 48-31 roll on top-rated MLB money-line picks through eight weeks, returning over $1,100 for $100 players. Anyone following it has seen huge returns.

Now, the model has set its sights on Padres vs. Cardinals and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Cardinals vs. Padres:

  • Padres vs. Cardinals money line: St. Louis -115, San Diego +100
  • Padres vs. Cardinals run line: San Diego -1.5 (+160)
  • Padres vs. Cardinals over-under: 9 runs
  • Padres vs. Cardinals tickets: See tickets at StubHub
  • SD: Padres are 4-0 in their last four road games
  • STL: Cardinals are 6-2 in their last eight overall

Why you should back the Padres 

Third baseman Manny Machado (elbow) is expected to return to the lineup after missing the past two games. Machado has good strength to all parts of the field with some home run power in his swing. The five-time All-Star also plays terrific defense in the corner and owns a rocket of an arm. Machado leads the team in batting average (.357), home runs (8), RBIs (27) and hits (60).

First baseman Eric Hosmer has a smooth left-handed stroke with patience at the dish. Hosmer can hit for average but owns a solid glove in the corner. The one-time All-Star displays an all-around game and provides a nice throwing target at first base. Hosmer has a batting average of .321 with four home runs and 24 RBIs. 

Why you should back the Cardinals

Second baseman Tommy Edman is a solid switch hitter in the lineup for St. Louis. Edman is patient at the plate and owns a line-drive swing. The 27-year-old has solid speed and is a threat to steal a few bases. Edman also has sound instincts on the defensive end, constantly being in the right position. He has a batting average of .278 with four home runs and 21 RBIs.

Third baseman Nolan Arenado is another offensive threat. Arenado has amazing hands, that allow him to consistently make contact with the ball. The six-time All-Star has natural home-run power and run-producing qualities. Arenado is second on the team in home runs (9) and RBIs (32). 

How to make Cardinals vs. Padres picks

SportsLine's model is leaning under on the total, projecting 8.8 combined runs. It also says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Padres vs. Cardinals? And which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.