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Madison Square Garden hosts an Eastern Conference tilt between the Indiana Pacers and the New York Knicks on Tuesday. The Pacers are 14-23 this season, and 3-14 on the road, while the Knicks enter in at 17-20 and 7-11 at home. Julius Randle, Nerlens Noel and Mitchell Robinson are listed as questionable for the Knicks, with Derrick Rose and Kemba Walker out. Malcolm Brogdon, Caris LeVert, Chris Duarte, Goga Bitadze and Jeremy Lamb are out for Indiana.

Caesars Sportsbook lists New York as a 3.5-point home favorite, and tip-off is scheduled for 7:30 p.m. ET. The total number of points Vegas thinks will be scored, or the Over-Under, is 207 in the latest odds. Before you make any NBA predictions with the Pacers vs. Knicks match-up, be sure to see the NBA predictions and betting advice from SportsLine's proven computer model. 

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 12 of the 2021-22 NBA season on a stunning 50-27 roll on all top-rated NBA picks, returning almost $2,000. Anyone following it has seen huge returns.

Now, the model has set its sights on Knicks vs. Pacers and revealed its NBA picks and predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and betting lines for Pacers vs. Knicks:

  • Pacers vs. Knicks spread: Knicks -3.5
  • Pacers vs. Knicks over-under: 207 points
  • Pacers vs. Knicks money line: Knicks -150, Pacers +130
  • IND: The Pacers are 7-10 against the spread in road games
  • NYK: The Knicks are 6-12 against the spread in home games

Why the Knicks can cover

The Knicks have the benefit of home-court advantage, and the Pacers struggle mightily away from Indianapolis. The Pacers have the fourth-worst road record in the NBA this season, and Indiana has been out-scored by more than four points per 100 possessions in road games. On the whole, Indiana is also No. 26 in the NBA in three-point accuracy, and the Pacers are in the bottom 10 of the NBA in free throw creation on offense and free throw prevention on defense. 

The Knicks produce more than 21 free throw attempts per game on offense, and New York ranks in the top 10 of the NBA in preventing free throw attempts on defense. Tom Thibodeau's team ranks in the top three in field goal percentage allowed and two-point percentage allowed, and the Knicks can match up effectively against Indiana.

Why the Pacers can cover

Indiana is shooting 54.3 percent on 2-point attempts, ranking in the top five of the NBA. The Pacers also put pressure on the offensive glass, securing 29.9 percent of available rebounds and producing 14.4 second-chance points per game. Indiana moves the ball well, generating 23.8 assists per game, and the Pacers rank in the top 10 in fast-break points (13.3 per game) and points in the paint (48.6 per game). New York is in the bottom five in turnover creation, allowing Indiana's offense to flow freely. 

On defense, the Pacers are tremendous near the rim, ranking in the top five in defensive rebound rate (74.3 percent) and leading the NBA in blocked shots (5.9 per game). Indiana is also in the top three of the league in assists allowed (22.0 per game) and 3-pointers allowed (10.8 per game). The Pacers could also benefit from the Knicks ranking in the bottom five of the NBA in assists, field-goal percentage and 2-point percentage.

How to make Pacers vs. Knicks picks

SportsLine's model is leaning over on the total. The model also says one side of the spread hits well over 60 percent of the time. You can only get the model's NBA picks at SportsLine.

So who will win Knicks vs. Pacers? And which side of the spread hits well over 60 percent of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its NBA picks, and find out.