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The Detroit Pistons will take on the Portland Trail Blazers at 7 p.m. ET on Monday at Little Caesars Arena. Detroit is 19-52 overall and 11-23 at home, while Portland is 26-44 overall and 9-26 on the road. The Trail Blazers have lost eight straight road games; the Pistons have lost five of their last six games overall. 

Detroit is favored by seven-points in the latest Pistons vs. Trail Blazers odds from Caesars Sportsbook, while the over-under is set at 222.5. Before entering any Trail Blazers vs. Pistons picks, you'll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past three-plus seasons. The model enters Week 21 of the 2021-22 NBA season on a stunning 78-48 roll on all top-rated NBA picks, returning over $2,400. Anyone following it has seen huge returns.

Now, the model has set its sights on Pistons vs. Trail Blazers. You can head to SportsLine to see its picks. Here are several NBA betting lines for Pistons vs. Trail Blazers:

  • Pistons vs. Trail Blazers spread: Pistons -7
  • Pistons vs. Trail Blazers over-under: 222.5 points

What you need to know about the Pistons

Detroit wrapped up a three-game road trip with a 113-109 loss to Cleveland on Saturday. The Pistons have now lost five of their last six games, despite Jerami Grant pouring in a season-high 40 points in the loss to the Cavaliers. Saddiq Bey, who scored 51 points in a win over Orlando on Thursday, added 20 points against Cleveland.

The Pistons are trying to build a promising future with young players, as Grant is the only player in the lineup who is not a rookie or second-year player. He leads the team with 19.5 points per game, while Cade Cunningham is adding 16.9 points, 5.9 rebounds and 5.4 assists. Grant is going to miss Monday's game due to a knee injury, so the Pistons will need a big game from Cunningham. 

What you need to know about the Trail Blazers

Portland is now riding a four-game losing streak and has lost 10 of its last 11 games overall. The Trail Blazers never led in Sunday's 129-98 loss at Indiana. They have been dealing with injury issues throughout the season, as Damian Lillard, Jusuf Nurkic and Anfernee Simons are all out.

Shooting guard Josh Hart led Portland with 26 points in Sunday's loss. He has been a bright spot during the rough stretch, averaging 28.6 points over his last five games. The Trail Blazers have won six of their last seven games against the Pistons. 

How to make Pistons vs. Trail Blazers picks

The model has simulated Pistons vs. Trail Blazers 10,000 times and the results are in. We can tell you that the model is leaning under, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You can only see the pick at SportsLine.

So who wins Trail Blazers vs. Pistons? And which side of the spread hits almost 70 percent of the time? Visit SportsLine now to find out, all from the model that has crushed its NBA picks.